Chemistry of Heterocyclic Compounds

, Volume 35, Issue 1, pp 58–63 | Cite as

Investigations on furopyridines. 10. Synthesis of 4-N-substituted 1H-furo[3,4]pyridin-3-ones

  • I. S. Arustamova
  • V. T. Piven'


2-Amino or 2-hydrazino derivatives of pyridine or pyridinopyrazole were obtained by amination or hydrazination of 2-chloro-3-cyano-4-methoxy-6-methylpyridine. Acid hydrolysis of these derivatives leads to heterocyclization with formation of 4-amino-1H-furo[3,4-c]pyridines or pyrazolo[3,4-b]pyridine. The possibility to synthesize 4-arylamino-1H-furo[3,4-c]-pyridines from 4-chloro-6-methyl-1H-furo[3,4-c]-pyridine has been shown.


Hydrolysis Organic Chemistry Pyridine Acid Hydrolysis Furopyridines 
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© Kluwer Academic/Plenum 1999

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  • I. S. Arustamova
  • V. T. Piven'

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