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Chemistry of Heterocyclic Compounds

, Volume 35, Issue 1, pp 58–63 | Cite as

Investigations on furopyridines. 10. Synthesis of 4-N-substituted 1H-furo[3,4]pyridin-3-ones

  • I. S. Arustamova
  • V. T. Piven'
Article

Abstract

2-Amino or 2-hydrazino derivatives of pyridine or pyridinopyrazole were obtained by amination or hydrazination of 2-chloro-3-cyano-4-methoxy-6-methylpyridine. Acid hydrolysis of these derivatives leads to heterocyclization with formation of 4-amino-1H-furo[3,4-c]pyridines or pyrazolo[3,4-b]pyridine. The possibility to synthesize 4-arylamino-1H-furo[3,4-c]-pyridines from 4-chloro-6-methyl-1H-furo[3,4-c]-pyridine has been shown.

Keywords

Hydrolysis Organic Chemistry Pyridine Acid Hydrolysis Furopyridines 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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© Kluwer Academic/Plenum 1999

Authors and Affiliations

  • I. S. Arustamova
  • V. T. Piven'

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