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Chemistry of Heterocyclic Compounds

, Volume 35, Issue 1, pp 51–57 | Cite as

Investigations on imidazoles 99. Synthesis and some conversions of esters of 4-nitro-5-imidazolylmalonic,-acetoacetic, and-cyanoacetic acids

  • P. M. Kochergin
  • L. A. Reznichenko
  • R. N. Gireva
  • E. V. Aleksandrova
Article

Abstract

Some esters of 1-alkyl(1,2-dialkyl)-4-nitro-5-imidazolylmalonic,-acetoacetic, and-cyanoacetic acids have been synthesized by the reaction of 5-chloro(bromo)-1-alkyl(1,2-dialkyl)-4-nitroimidazoles with ethyl esters of carboxylic acids indicated. Some conversions of the compounds obtained have been studied, including ketone and acid decomposition, synthesis of derivatives at the COOH and CO groups, and hydrogenation to 4-aminoimidazole derivatives.

Keywords

Hydrogenation Ester Ethyl Organic Chemistry Ketone 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Kluwer Academic/Plenum 1999

Authors and Affiliations

  • P. M. Kochergin
  • L. A. Reznichenko
  • R. N. Gireva
  • E. V. Aleksandrova

There are no affiliations available

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