Advertisement

Journal of Assisted Reproduction and Genetics

, Volume 11, Issue 2, pp 104–106 | Cite as

Effect of Chlamydial antibodies on the outcome of in vitro fertilization (IVF) treatment

  • Isik Tasdemir
  • Murat Tasdemir
  • Hideya Kodama
  • Kazuko Sekine
  • Toshinobu Tanaka
Clinical Assisted Reproduction

Abstract

Objective

Our objective was to study the relationship between the presence of Chlamydia trachomatisantibodies and the success of IVF treatment.

Design

We evaluated 118 in vitro fertilization and embryo transfer (IVF-ET) treatment cycles from 51 couples with a history of infertility lasting for at least 2 years. All women starting a treatment cycle had their serum chlamydial antibody titers measured by indirect immunofluorescent technique. All patients received similar ovarian stimulation regimens and the oocytes collected were inseminated with similar concentrations of motile sperm. Clinical data from couples where the female partner had C. trachomatisab titers ≥40 have been compared with the equivalent data from couples where the female partner had C. trachomatisab titers <40.

Results

There was no statistically significant difference between the two groups concerning age, infertility period, oocytes collected, oocytes fertilized, and fertilization rate, and the pregnancy rates were comparable.

Conclusion

Previous exposure to C. trachomatisdid not alter the success rate of IVF-ET.

Key words

chlamydial antibodies in vitro fertilization/embryo transfers tubal infertility 

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. 1.
    Thompson SE, Washington AE: Epidemiology of sexually transmitted Chlamydia trachomatis infections. Epidemiol Rev 1983;5:96PubMedGoogle Scholar
  2. 2.
    Gump DW, Gibson M, Ashikaga T: Evidence of prior pelvic inflammatory disease and its relationship to Chlamydia trachomatis antibody and intrauterine contraceptive device use in infertile women. Am J Obstet Gynecol 1983;146:153PubMedGoogle Scholar
  3. 3.
    Tasdemir I, Tasdemir M, Kodama H, Fukuda J, Toshihiko M, Sekine K, Higuchi M: Chlamydial serology and tubal infertility. Jpn J Fertil Steril 1993;38(3):37Google Scholar
  4. 4.
    Tasdemir M, Tasdemir I, Kodama H, Fukuda J, Matsui T, Sekine K, Higuchi M: Should we transfer bad quality embryo together with good ones to increase the number of embryos transferred and pregnancy rate in turn. Jpn J Fertil Steril 1993;38(3):9Google Scholar
  5. 5.
    Kawamura A: National Institution of Health Methodology of Virology, Ed 2. Tokyo, Maruzen, 1973, p 297Google Scholar
  6. 6.
    Mardh PA, Ripa KT, Svensson L, Westrom L: Chlamydia trachomatis infection in patients with acute salpingitis. N Engl J Med 1977;296:1377PubMedGoogle Scholar
  7. 7.
    Trehorne JD, Ripa KT, Mardh PA, Svensson L, Westrom L, Daraugar S: Antibodies to Chlamydia trachomatis in acute salpingitis. Br J Vener Dis 1979;55:26PubMedGoogle Scholar
  8. 8.
    Gjonnaes H, Dalaker K, Anestad G, Mardh PA, Kuile G, Bergan T: Pelvic inflammatory diseases: Etiologic studies with emphasis on chlamydial infection. Obstet Gynecol 1982;59:550PubMedGoogle Scholar
  9. 9.
    Anestad G, Lunde O, Moen M, Dalaker K: Infertility and chlamydia infection. Fertil Steril 1987;48:787PubMedGoogle Scholar
  10. 10.
    Moss TR: Chlamydia trachomatis: importance in in vitro fertilization. JR Soc Med 1984;77:70Google Scholar
  11. 11.
    Rowland GF, Forsey T, Moss JR, Steptoe PC, Hewitt J, Darougar S: Failure of in vitro fertilization and embryo replacement following infection with chlamydia trachomatis. J Vitro Fert Embryo Transfer 1985;2:151CrossRefGoogle Scholar
  12. 12.
    Torode HW, Wheeler PA, Saunders DM, McPetrie RA, Medcalf SC, Ackerman VP: The role of chlamydial antibodies in an in vitro fertilization program, Fertil Steril 1987;48:987PubMedGoogle Scholar

Copyright information

© Plenum Publishing Corporation 1994

Authors and Affiliations

  • Isik Tasdemir
    • 1
  • Murat Tasdemir
    • 1
  • Hideya Kodama
    • 1
  • Kazuko Sekine
    • 1
  • Toshinobu Tanaka
    • 1
  1. 1.Department of Obstetrics and GynecologyAkita University School of MedicineAkitaJapan

Personalised recommendations