Abstract
Trabecular bone mineral content was assessed by quantitative computed tomography in eleven young adults with phenylketonuria who had been treated from early childhood with a diet restricted in natural protein and supplemented with amino acids, minerals and vitamins. There was a significant reduction in the bone mineral content of patients compared with the normal population. Prospective studies are indicated in younger patients to ensure optimum bone mineralisation is achieved by adulthood.
Similar content being viewed by others
References
Feinberg SB, Fisch RO (1961) Roentgenologic findings in growing long bones in Phenylketonuria. Radiology 78: 394
Holt JF, Allen RJ (1967) Radiologic signs in the primary aminoacidurias. Ann Radiol 10: 317
Woodring JH, Rosenbaum HD (1981) Bone changes in phenylketonuria reassessed. Am J Roentgenol 137:241.
Kindt E Halvorsen S, Lie SO (1987) Does a marginal protein intake result in osteoporosis? J Inher Metab Dis 10: 195
Committee on Medical Aspects of Food Policy (1979) Recommended daily amount of food energy and nutrients for groups of people in the United Kingdom. DHSS London Report, No. 15
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Carson, D.J., Greeves, L.G., Sweeney, L.E. et al. Osteopenia and phenylketonuria. Pediatr Radiol 20, 598–599 (1990). https://doi.org/10.1007/BF02129064
Received:
Accepted:
Issue Date:
DOI: https://doi.org/10.1007/BF02129064