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Outcome of assisted reproduction technology in infertile couples of consanguineous marriage

  • Clinical Assisted Reproduction
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Abstract

Purpose: The outcome of pregnancies resulting from assisted reproduction technology does not seem to differ from the outcome of those arising from spontaneous natural conception.

Methods: There is increased risk of chromosomal abnormality in spontaneous natural pregnancies resulting from consanguineous marriage, with consequent higher rates of miscarriage, stillbirth, and congenital abnormalities.

Results: This study has shown a trend of an increased miscarriage rate (but not statistically significant) in pregnancies achieved in infertile couples of consanguineous marriages by assisted reproductive technology.

Conclusions: Selecting embryos for transfer on the basis of their morphology does not appear to reduce the risk of chromosomal abnormality in these couples.

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Authors and Affiliations

  1. IVF Centre, Maternity Hospital, Kuwait City, Kuwait

    P. E. Egbase, M. Al-Sharhan, S. Al-Othman & M. Al-Mutawa

  2. Academic Unit of Obstetrics & Gynaecology, Royal London Hospital, Whitechapel, London El, UK

    P. E. Egbase & J. G. Grudzinskas

Authors
  1. P. E. Egbase
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  2. M. Al-Sharhan
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  3. S. Al-Othman
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  4. M. Al-Mutawa
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  5. J. G. Grudzinskas
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Egbase, P.E., Al-Sharhan, M., Al-Othman, S. et al. Outcome of assisted reproduction technology in infertile couples of consanguineous marriage. J Assist Reprod Genet 13, 279–281 (1996). https://doi.org/10.1007/BF02070138

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  • DOI: https://doi.org/10.1007/BF02070138

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