Pediatric Radiology

, Volume 21, Issue 6, pp 404–405 | Cite as

Pulmonary changes in congenital syphilis

  • R. Austin
  • R. E. Melhem


Three of seven infants afflicted with congenital syphilis at our institution in the past five years showed diffuse pulmonary infiltrates. These persisted long after adequate antibiotic treatment of the primary infection. Review of pathologic literature suggests these infiltrates represent pulmonary immaturity, extramedullary hematopoiesis, and interstitial scarring.


Public Health Antibiotic Treatment Syphilis Primary Infection Pulmonary Infiltrate 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


  1. 1.
    Rolfs RT, Nakashima AK (1990) Epidemiology of primary and secondary syphilis in the United States, 1981 through 1989. JAMA 264: 1432CrossRefPubMedGoogle Scholar
  2. 2.
    Teberg A, Hodgman JE (1973) Congenital syphilis in newborn. Calif Med 118: 5Google Scholar
  3. 3.
    Hira SK, et al. (1985) Early congenital syphilis: clinico-radiologic features in 202 patients. Sex Trans Diseases 12: 177Google Scholar
  4. 4.
    Oppenheimer EH, Hardy JB (1971) Congenital syphilis in the newborn infant: Clinical and pathological observations in recent cases. Hopkins Med J 129: 63Google Scholar
  5. 5.
    Oppenheimer EH, Dahms BB (1981) Congenital syphilis in the fetus and neonate. Perspect Pediatr Pathol 6: 115PubMedGoogle Scholar
  6. 6.
    Bradford BF, et al. (1988) Usual and unusual radiologic manifestations of acquired immunodeficiency syndrome (AIDS) and human immunodeficiency virus (HIV) infection in children. Radiol Clin North Am 26: 341PubMedGoogle Scholar
  7. 7.
    Amodio JB, Abramson S, Berdon WE, Levy J (1987) Pediatric AIDS. Semin Roentgenol 22: 66PubMedGoogle Scholar
  8. 8.
    Zimmerman BL, Haller JO, Price AP, Thelmo WL, Fikrig S (1987) Children with AIDS — Is pathologic diagnosis possible based on chest radiographs? Pediatr Radiol 17: 303PubMedGoogle Scholar

Copyright information

© Springer-Verlag 1991

Authors and Affiliations

  • R. Austin
    • 1
  • R. E. Melhem
    • 1
  1. 1.Department of RadiologyUniversity of South Alabama, College of MedicineMobileUSA

Personalised recommendations