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The fibrous metaphyseal defect in early stage

Differential diagnosis to metaphysitis

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Abstract

In a 22-month-old boy a fibrous metaphyseal defect (FMD) was diagnosed by radiological follow-up examinations. The initial radiological finding could not be differentiated from metaphysitis because of its early manifestation and stage. Eleven months later, magnetic resonance imaging (MRI) with Gadolinium (Gd)-DTPA demonstrated a small central area of increased signal intensity. Based on known angiographic findings with fibrous metaphyseal defects, one may hypothesize that this is best explained by a hypervascularized area.

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Dietlein, M., Benz-Bohm, G. & Widemann, B. The fibrous metaphyseal defect in early stage. Pediatr Radiol 22, 461–462 (1992). https://doi.org/10.1007/BF02013513

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  • DOI: https://doi.org/10.1007/BF02013513

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