Abstract
The results of MRI and MIBG scintigraphy performed on the spine of 14 children with neuroblastoma are reported. In 6 cases of diffuse spinal bone marrow tumor infiltration, diagnosis is easier with MIBG scintigraphy than with MRI. In 5 cases, MRI detected hyposignal of the vertebral body without any spinal abnormality on MIBG scintigraphy. A discussion of the reasons for negative MIBG scintigraphy is presented and in these 5 cases, it is suggested that a lateral view of MIBG scintigraphy and HMDP-Tc99m scintigraphy may be performed, even vertebral body biopsy in order to assess bone marrow tumoral infiltration.
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Najean, B.B., Siles, S., Panuel, M. et al. Value of MRI and MIBG-I123 scintigraphy in the diagnosis of spinal bone marrow involvement in, neuroblastoma in children. Pediatr Radiol 22, 443–446 (1992). https://doi.org/10.1007/BF02013507
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DOI: https://doi.org/10.1007/BF02013507