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The echogenic ependymal wall in intraventricular hemorrhage: Sonographic-pathologic correlation

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Abstract

Fifty-one patients with ultrasound diagnosis of intraventricular hemorrhage (Grades III and IV) were studied retrospectively for the presence of ependymal echogenicity. The sonographic findings were then correlated with histologic findings in six autopsy cases. Forty-one out of fifty-one newborns with intraventricular hemorrhage developed ependymal echogenicity on serial ultrasound studies. This echogenicity appeared approximately seven days after the hemorrhagic event and ulsually disappeared in about six weeks. Histologic examination revealed disruptions in the ependyma with proliferation and extension of subependymal glial cells onto the ventricular surface in those cases in which ependymal echogenicity was present at the time of death. This layer of proliferating subependymal glial cells may account for the ependymal echogenicity.

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References

  1. Papile L-A, Burstein J, Burstein R, Koffler H (1978) Incidence and evolution of subependymal and intraventricular hemorrhage: a study of infants with birth weights less than 1,500 gm. J Pediatr 92: 529

    PubMed  Google Scholar 

  2. Burstein J, Papile L-A, Burstein R (1979) Intraventricular hemorrhage and hydrocephalus in premature newborns: a prospective study with C. T. AJR 132: 631

    PubMed  Google Scholar 

  3. Ahmann PA, Lazzarra A, Dykes FD, Brann AW, Schwartz J (1980) Intraventricular hemorrhage: incidence and outcome. Ann Neurol 7: 118

    Article  PubMed  Google Scholar 

  4. Allan WC, Holt PJ, Sawyer LR, Tito AM, Meade SK (1982) Ventricular dilatation after neonatal periventricular-intraventricular hemorrhage: natural history and therapeutic implications. AJDC 136: 589

    PubMed  Google Scholar 

  5. Larroche J-C (1972) Post-haemorrhagic hydrocephalus in infancy: anatomic study. Biol Neonate 20:287

    PubMed  Google Scholar 

  6. Sauerbrei EE, Digney M, Harrison PB, Cooperberg PL (1981) Ultrasonic evaluation of neonatal intracranial hemorrhage and its complications. Radiology 139: 677

    PubMed  Google Scholar 

  7. Rumack CM, Johnson MJ (1984) Perinatal and infant brain imaging. Yearbook Medical Publishers, Chicago, p 123

    Google Scholar 

  8. Sherwood A, Hopp A, Smith JF (1978) Cellular reaction to subependymal plate haemorrhage in the human neonate. Neuropathol Appl Neurobiol 4: 245

    PubMed  Google Scholar 

  9. Milhorat TH, Clark RG, Hammock MK, McGrath PP (1970) Structural and permeability changes in the ependyma and surrounding brain favoring equilibration in progressive hydrocephalus. Arch Neurol 22: 397

    PubMed  Google Scholar 

  10. Weller RO, Wisniewski H (1969) Histological and ultrastructural changes with experimental hydrocephalus in adult rabbits. Brain 92: 819

    PubMed  Google Scholar 

  11. Weller RO, Wisniewski H, Shulman K, Terry RD (1971) Experimental hydrocephalus in young dogs: histological and ultrastructural study of the brain tissue damage. J Neuropathol Exp Neurol 30: 613

    PubMed  Google Scholar 

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Author notes

  1. G. Gaisie

    Present address: Department of Radiology, Akron Children's Medical Center, 281 Locust Street, 44308, Akron, Ohio, USA

  2. M. S. Roberts

    Present address: Department of Radiology, Medical Center Hospital Vermont, 05401, Burlington, Vermont, USA

Authors and Affiliations

  1. Department of Radiology, UNC School of Medicine, Chapel Hill, North Carolina, USA

    G. Gaisie, M. S. Roberts & J. H. Scatliff

  2. Department of Pathology, UNC School of Medicine, Chapel Hill, North Carolina, USA

    T. W. Bouldin

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  1. G. Gaisie
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  2. M. S. Roberts
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  3. T. W. Bouldin
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  4. J. H. Scatliff
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Gaisie, G., Roberts, M.S., Bouldin, T.W. et al. The echogenic ependymal wall in intraventricular hemorrhage: Sonographic-pathologic correlation. Pediatr Radiol 20, 297–300 (1990). https://doi.org/10.1007/BF02013158

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  • DOI: https://doi.org/10.1007/BF02013158

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