Skip to main content
Log in

Rational use of CT in acute pyelonephritis: Findings and relationships with reflux

  • Published:
Pediatric Radiology Aims and scope Submit manuscript

Abstract

Enhanced renal CT scanners were performed in 38 children (82% girls) to rule out acute pyelonephritis. Patients were divided in 2 groups on the basis of clinical presentation and bacteriology data. In patients of group A (n=16, preliminary study), upper urinary tract infection (UTI) was certain. CT confirmed the diagnosis in all but 3 patients (a 2-year-old child and 2 patients with UTI developed on prior obstruction). In subsequently studied patients of group B (n=22), clinical findings or bacteriology data were negative or questionable. CT made the diagnosis of acute pyelonephritis in 11 patients. As well as DMSA scintigraphy, CT scanner can help to diagnose or to rule out upper UTIs in difficult cases. In all boys of both groups, ipsilateral vesico-ureteric reflux (VUR) was found by subsequent voiding cystourethrography (VCUG) on the side of pyelonephritis. In girls, this correlation was shown in only 7 of the 25 kidneys with pyelonephritis. This result supports the hypothesis of a gender-dependent contamination. We believe that absence of radiologic reflux cannot exclude the possibility of bacterial crossings of ureteric meatus capable to lead to genuine upper UTIs.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. Montgomery P, Kuhn JP, Afshani E (1987) CT evaluation of severe renal inflammatory disease in children. Pediatr Radiol 17: 216–222

    PubMed  Google Scholar 

  2. Soulen MC, Fishman EK, Goldman SM, Gatewood OMB (1989) Bacterial renal infection: role of CT. Radiology 171:703–707

    PubMed  Google Scholar 

  3. Morehouse HT, Weiner SN, Hoffman JC (1984) Imaging in inflammatory disease of the kidney. AJR 143:135–141

    PubMed  Google Scholar 

  4. Greenfield SP, Montgomery P (1987) Computerized tomography and acute pyelonephritis in children. Urology 29:137–140

    Article  PubMed  Google Scholar 

  5. Sty JR, Wells RG, Starshak RJ, Schroeder BA (1987) Imaging in acute renal infection in children. AJR 148:471–477

    PubMed  Google Scholar 

  6. Tsugaya M, Hirao N, Sakagami H, Ohtaguro K, Washida H (1992) Renal cortical scarring in acute pyelonephritis. Br J Urol 69:245–249

    PubMed  Google Scholar 

  7. Jequier S, Jequier JC (1989) Reliability of voiding cystourethrography to detect reflux. AJR 153:807–810

    PubMed  Google Scholar 

  8. Paltiel HJ, Rupich RC, Kiruluta HG (1992) Enhanced detection of vesicoureteral reflux in infants and children with use of cyclic voiding cystourethrography. Radiology 184:753–755

    PubMed  Google Scholar 

  9. Kangarloo H, Gold RH, Fine RN, Diament MJ, Boechat MI (1985) Urinary tract infection in infants and children evaluated by ultrasound. Radiology 154:367–373

    PubMed  Google Scholar 

  10. Lebowitz RL (1986) The detection of vesicoureteral reflux in the child. Invest Radiol 21:519–531

    PubMed  Google Scholar 

  11. Winberg J, Bollgren I, Källenius G, Möllby R, Svenson SB (1982) Clinical pyelonephritis and focal renal scarring. Pediatr Clin North Am 29:801–814

    PubMed  Google Scholar 

  12. Rushton GH, Majd M, Jantausch B, Wiedermann BL, Belman AB (1992) Renal scarring following reflux and nonreflux pyelonephritis in children: evaluation with technetium-dimercaptosuccinic acid scintigraphy. J Urol 147:1327–1332

    PubMed  Google Scholar 

  13. Rushton HG, Winberg J, Jodal U, Roberts JA, O'Hanley P (1990) Pyelonephritis: pathogenesis and management update. Dialogues in Pediatric Urology 13 (no2):1–8

    Google Scholar 

  14. Slotki IN, Asscher AW (1982) Prevention of scarring in experimental pyelonephritis in the rat by early antibiotic therapy. Nephron 30:262–268

    PubMed  Google Scholar 

  15. Kass EJ, Fink-Bennett D, Cacciarelli AA, Balon H, Pavlock S (1992) The sensitivity of renal scintigraphy and sonography in detecting nonobstructive acute pyelonephritis. J Urol 148:606–608

    PubMed  Google Scholar 

  16. Silver TM, Kass EJ, Thornbury JR, Konnak JW, Wolfman MG (1976) The radiological spectrum of acute pyelonephritis in adults and adolescents. Radiology 118:65–71

    PubMed  Google Scholar 

  17. Gordon I (1987) Indications for 99m technetium dimercaptosuccinic acid scan in children. J Urol 137:464–467

    PubMed  Google Scholar 

  18. Elison BS, Taylor D, Van Der Wall H, Pereira JK, Cahill S, Rosenberg AR, Farnsworth RH, Murray PC (1992) Comparison of DMSA scintigraphy with intravenous urography for the detection of renal scarring and its correlation with vesicoureteric reflux. Br J Urol 69:294–302

    PubMed  Google Scholar 

  19. Cukier J, Terdjman S, Zhong Xun L, Beurton D, Charbit L (1988) La correction chirurgicale des reflux vésico-urétéraux intermittents sans reflux radiologiquement décelable. J Urol (Paris) 94:319–322

    Google Scholar 

  20. Kirks D (1983) Computed tomography of pediatric urinary tract disease. Urol Radiol 5:199–208

    PubMed  Google Scholar 

  21. Decter RM, Roth DR, Gonzales Jr ET (1988) Vesicoureteral reflux in boys. J Urol 40:1089–1091

    Google Scholar 

  22. Steele BT, De Maria J (1992) A new perspective on the natural history of vesicoureteric reflux. Pediatrics 90:30–32

    PubMed  Google Scholar 

  23. Lebowitz RL, Mandell J (1987) Urinary tract infection in children: putting radiology in its place. Radiology 165:1–9

    Google Scholar 

  24. Lapides J, Diokno AC (1970) Persistence of the infant bladder as a cause for urinary infection in girls. J Urol 103:243–248

    PubMed  Google Scholar 

  25. Wiswell TE, Smith FR, Bass JW (1985) Decreased incidence of urinary tract infections in circumcised male infants. Pediatrics 75: 901–903

    PubMed  Google Scholar 

  26. Avni EF, Gallety E, Rypens F, Hall M, Dedeire S, Schulman CC (1992) A hypothesis for the higher incidence of vesico-ureteral reflux and primary megaureters in male babies. Pediatr Radiol 22:1–4

    Article  PubMed  Google Scholar 

  27. Roberts JA, Suarez GM, Kaack B, Känellius G, Svenson SB (1985) Experimental pyelonephritis in the monkey VII: Ascending pyelonephritis in the absence of vesicoureteral reflux. J Urol 133:1068–1075

    PubMed  Google Scholar 

  28. Elo J, Tallgren LG, Alfthan O, Sarna S (1983) Character of urinary tract infections and pyelonephritic renal scarring after antireflux surgery. J Urol 129:343–346

    PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Dacher, J.N., Boillot, B., Eurin, D. et al. Rational use of CT in acute pyelonephritis: Findings and relationships with reflux. Pediatr Radiol 23, 281–285 (1993). https://doi.org/10.1007/BF02010915

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF02010915

Keywords

Navigation