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Ofloxacin intravenous

Compatibility with other antibacterial agents

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Abstract

The physical and chemical compatibility of ofloxacin (infusion solution 100 ml=200 mg) with amoxicillin, amoxicillin+clavulanic acid, flucloxacillin, tobramycin, gentamicin, clindamycin, vancomycin, ceftazidime and piperacillin was investigated. Upon admixture with flucloxacillin a precipitate formed between 7 and 24 hours. No other physical or chemical incompatibilities were observed with any of the other combinations. Ofloxacin may be safely combined with the tested antimicrobial drugs, except for flucloxacillin.

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Janknegt, R., Stratermans, T., Cilissen, J. et al. Ofloxacin intravenous. Pharmaceutisch Weekblad Scientific Edition 13, 207–209 (1991). https://doi.org/10.1007/BF01988876

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  • DOI: https://doi.org/10.1007/BF01988876

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