Pharmaceutisch Weekblad

, Volume 13, Issue 3, pp 137–141 | Cite as

Small-scale preparations in Sweden

Extemporaneous preparations and stock preparations at eleven community pharmacies
  • Å. Kettis
  • D. Isacson
  • K. Bingefors
  • G. Eriksson


Small-scale preparations,i.e. non-registered drugs that are extemporaneously prepared for each patient or made in larger batches for stock keeping, form a small but important group of drugs, especially for patients with rare diseases or allergies. Small-scale preparations are not included in the otherwise comprehensive statistics compiled by the National Corporation of Swedish Pharmacies and this makes knowledge of the use of these drugs limited. The occurrence of small-scale preparations was studied at eleven community pharmacies over a three-year period (1987–1989) by analysis of the orders from the pharmacies to the four production units of the National Corporation of Swedish Pharmacies in the first quarter of each study year. The number of small-scale preparations dispensed were compared with the total sales of drugs at each pharmacy. The proportion of small-scale preparations in the total drug sales was about 1.5% throughout the study period, but there were fluctuations over time at the individual pharmacies. The most common dosage forms were creams, liniments and mixtures. Dermatological drugs in different dosage forms were the most frequent (almost 50%). This was probably because of the necessity for a great variety of different strengths among these drugs.


Pharmacy services, community Drug compounding Drug utilization Sweden 


Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.


  1. 1.
    Nightingale SL. Orphan drugs. Am Fam Phys 1986;33:235–6.Google Scholar
  2. 2.
    Nilsson JLG, Gunnarsson B. Fabrikantlösa läkemedel i Sverige behöver bättre dokumentation och klarare lagstiftning [There is a need for better documentation and clearer legislation for ‘orphan drugs’ in Sweden]. Lakartidningen 1986;83:3829–30.Google Scholar
  3. 3.
    Gunnarsson B. Apoteksbolaget tillverkar ‘fabrikantlösa läkemedel’ — som annars inte vore tillgängliga [The National Corporation of Swedish Pharmacies is manufacturing ‘orphan drugs’ which otherwise would not be available]. Svensk Farm Tidskr 1989;12:30–2.Google Scholar
  4. 4.
    Anonymous. Svensk Läkemedelsstatistik 1989 [Swedish statistics on medicines]. Stockholm: Apoteksbolaget AB, 1990.Google Scholar
  5. 5.
    Kristoferson K, Wessling A. Tre års receptundersökningar [Three years with the prescription survey]. Svensk Farm Tidskr 1977;81:309–16.Google Scholar
  6. 6.
    Jacobsson M, Kristoferson K. Diagnos — receptundersökningen [The diagnoses and therapy survey]. Svensk Farm Tidskr 1980;84:321–3.Google Scholar
  7. 7.
    Agenäs I, Dahlström M. Diagnos-Receptundersökningen [The diagnoses and therapy survey]. Lakartidningen 1983;80:1467–70.Google Scholar
  8. 8.
    Anonymous. Svensk Läkemedelsstatistik 1981 [Swedish statistics on medicines]. Stockholm: Apoteksbolaget AB, 1982.Google Scholar
  9. 9.
    Badeie F. Extemporeförskrivning inom öppenvården i C-län [The prescribing of small scale preparations in the outpatient care in the county of Uppsala]. Uppsala: Department of Social Pharmacy, 1988.Google Scholar
  10. 10.
    Gerstrøm E, Hamborg Jensen N. Magistrelle laegemidler I [Small-scale preparations I]. Farm Tidende 1980;90:821–36.Google Scholar
  11. 11.
    Gerstrøm E, Hamborg Jensen N. Magistrelle laegemidler II [Small-scale preparations II]. Farm Tidende 1980;90:845–8.Google Scholar
  12. 12.
    Bhanderi D. Magistrel laegemiddelproduktion [The manufacturing of small-scale preparations]. Farm Tidende 1981;91:25–32.Google Scholar
  13. 13.
    Torp E-K, Bonde Jensen T, Thygesen EM, Holm J. Magistrel Produktion [The manufacturing of smallscale preparations]. Farm Tidende 1981;91:453–61.Google Scholar
  14. 14.
    Finholt P, Fleming Petersen K, Sørensen O, Torud Y. En undersøkelse av apotekens magistrelle reseptur [A study of extemporaneous production in pharmacies]. Norsk Apotekerfor Tidskr 1977;85:490–9.Google Scholar
  15. 15.
    Finholt P, Seljeflot S, Torud Y. En undersøkelse av det magistrelle resepturarbeid i apotek [A study on extemporaneous production in pharmacies]. Norsk Apotekefor Tidskr 1978;86:66–75.Google Scholar
  16. 16.
    Sanders B. Het aandeel van ex-tempore-bereide voorschriften, van spécialités en van FNA-preparaten in de receptuur van een openbare apotheek [The proportion of extemporaneous preparations, spécialities and FNA-preparations at an outpatient pharmacy]. Pharm Weekbl 1976;111:127.Google Scholar
  17. 17.
    Cohen EH. Noodzaak en mogelijkheid van het chemisch-analytisch onderzoek in de apotheek [Chemical analysis in the pharmacy — necessity and possibilities]. Pharm Weekbl 1977;112:605–13.Google Scholar
  18. 18.
    Sanders B. Het aandeel van ex-tempore-bereide voorschriften, van spécialités en van FNA — preparaten in de receptuur van een openbare apotheek [The share of extemporaneous preparations, specialities and FNA- preparations at an out-patient pharmacy]. Pharm Weekbl 1978;113:1044.Google Scholar
  19. 19.
    Kolář J, Fekárová A, Špringer V, Bruštíková E. K problematice preskripce léku. Struktura preskripce individuálně připravovaných léků [On drug prescribing. Structure of prescriptions of individually prepared drugs]. Ceskoslovenske zdravotnictvci 1989;37:43–8.Google Scholar
  20. 20.
    Cox HLM, Elferink F, Kloeg PHAM. De plaats van de bereiding van geneesmiddelen in de openbare farmacie [The position of preparation of drugs within the out-patient pharmacy]. Pharm Weekbl 1988;123:453–6.Google Scholar
  21. 21.
    Anonymous. Varumeddelande från Apoteksbolaget [Information on products from the National Corportion of Swedish Pharmacies]. Apoteksbolaget AB, 1988:21.Google Scholar

Copyright information

© Royal Dutch Association for Advancement of Pharmacy 1991

Authors and Affiliations

  • Å. Kettis
    • 1
  • D. Isacson
    • 1
  • K. Bingefors
    • 1
  • G. Eriksson
    • 2
  1. 1.Department of Social PharmacyUppsala University, BMCUppsalaSweden
  2. 2.National Corporation of Swedish PharmaciesStockholmSweden

Personalised recommendations