Pharmaceutisch Weekblad

, Volume 14, Issue 4, pp 224–228 | Cite as

Cardiovascular drugs

  • Pieter Vermeij
Drugs in the Pipeline


Since the category of cardiovascular drugs comprises a considerable number of pharmacotherapeutic groups, an overview of future developments must necessarily be limited to those areas in which innovations are most likely to occur. Further extension of our knowledge of thrombolytic therapy may eventually lead to new choices of primary drugs. In the area of antiarrhythmic therapy, the clinical use of a number of drugs has been hampered by the pro-arrhythmogenic actions of these agents. The development of new class III anti-arrhythmics will continue, probably giving rise to new therapeutic options. In the vascular area a new group of drugs, the renin inhibitors, is likely to emerge for the treatment of hypertension. Moreover, exciting discoveries in vascular pharmacology should eventually translate into new pharmacotherapeutic approaches. Finally, the large-scale availability of blood fractions (coagulation factors) prepared by recombinant technology may help solve current shortages of products derived from donated blood.


Antiarrhythmic drugs Cardiovascular drug innovation Thrombolytics Renin inhibitors Recombinant blood coagulation factors 


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Copyright information

© Royal Dutch Association for Advancement of Pharmacy 1992

Authors and Affiliations

  • Pieter Vermeij
    • 1
  1. 1.Department of Clinical Pharmacy and ToxicologyUniversity Hospital LeidenRC Leidenthe Netherlands

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