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Chronic granulomatous disease: value of the newer imaging modalities

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Abstract

The contribution of computed tomography (CT), ultrasound (US), and nuclear medicine studies in the evaluation and management of seven patients with chronic granulomatous disease was retrospectively reviewed. These modalities proved valuable in detecting sites of infection, particularly in the abdomen. Three patients had liver abscesses, two had suppurative retroperitoneal lymphadenopathy, one had empyema, and one had a scrotal abscess. Furthermore, CT or US-guided percutaneous aspiration and/or drainage of infected material was successfully performed on three separate occasions in a single patient, obviating the need for surgery. The newer imaging modalities are useful in the prompt diagnosis and in some instances non-operative therapy of complications of chronic granulomatous disease.

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References

  1. Bachner RL, Nathan DG (1968) Quantitative nitroblue tetrazolium test in chronic granulomatous disease. N Engl J Med 278: 971

    Google Scholar 

  2. Bassani F, Capsoni F, Lazzarin A, Rossi A (1981) Chronic granulomatous disease. Pediatr Radiol 11: 105

    Google Scholar 

  3. Berendes H, Bridges RA, Good RA (1957) A fatal granulomatosis of childhood: clinical study of a new syndrome. Minn Med 40: 309

    Google Scholar 

  4. Caldicott WJH, Baehner RL (1968) Chronic granulomatous disease of childhood. AJR 103: 133

    Google Scholar 

  5. Chusid MJ (1978) Pyogenic hepatic abscess in infancy and childhood. Pediatrics 62: 554

    Google Scholar 

  6. Dilworth JA, Mandell GL (1977) Adults with chronic granulomatous disease of “childhood”. Am J Med 63: 233

    Google Scholar 

  7. Forbes GS, Hartman GW, Burke EC, Segura JW (1976) Genitourinary involvement in chronic granulomatousdisease of childhood. AJR 127: 683

    Google Scholar 

  8. Gold RH, Douglas SD, Preger L, Steinbach HL, Fudenberg HH (1969) Roentgenographic features of the neutrophil dysfunction syndromes. Radiology 92: 1045

    Google Scholar 

  9. Griscom NT, Kirkpatrick JA, Girdany BR, Berdon WE, Grand RJ, Mackie GG (1974) Gastric antral narrowing in chronic granulomatous disease of childhood. Pediatrics 54: 456

    Google Scholar 

  10. Grund KE, Klotter HJ, Lemmel EM (1982) Chronische Granulomatose als seltene Ursache rezidivierender Leberabszesse. Med Welt 33: 202

    Google Scholar 

  11. Johansen KS, Borregaard N, Koch C, Taudorf E, Wandall JH, Repine JE (1982) Chronic granulomatous disease presenting as xanthogranulomatous pyelonephritis in late childhood. J Pediatr 100: 98

    Google Scholar 

  12. Johnston RB, Jr, Newman SL (1977) Chronic granulomatous disease. Ped Clin North Am 24: 365

    Google Scholar 

  13. Landing BH, Shirkey HS (1957) A syndrome of recurrent infection and infiltration of viscera by pigmented lipid histocytes. Pediatrics 20: 431

    Google Scholar 

  14. Mark LK (1978) Chronic granulomatous disease in the adult. J Fam Prac 7: 445

    Google Scholar 

  15. Newlin N, Silver TM, Stuck KJ, Sandler MA (1981) Ultrasonic features of pyogenic liver abscesses. Radiology 139: 155

    Google Scholar 

  16. Preimesberger KF, Goldberg ME (1974) Acute liver abscess in chronic granulomatous disease of childhood. Radiology 110: 147

    Google Scholar 

  17. Quie PG, White JG, Holmes B, Good RA (1967) In vitro bactericidal capacity of human polymorphonuclear leukocytes: diminished activity in chronic granulomatous disease of childhood. J Clin Invest 46: 668

    Google Scholar 

  18. Rutenberg WD, Yang MC, Doberstyn EB, Bellanti JA (1977) Multiple leukocyte abnormalities in chronic granulomatous disease: a fimilial study. Pediatr Res 11: 158

    Google Scholar 

  19. Samuels LD (1971) Liver scans in chronic granulomatous disease of childhood. Pediatrics 48: 41

    Google Scholar 

  20. Sutcliffe J, Chrispin AR (1970) Chronic granulomatous disease. Br J Radiol 43: 110

    Google Scholar 

  21. Wolfson JJ, Quie PG, Laxdal SD, Good RA (1968) Roentgenologic manifestations in children with a genetic defect of polymorphonuclear leukocyte function. Radiology 91: 37

    Google Scholar 

  22. Wolfson JJ, Kane WJ, Laxdal SD, Good RA, Quie PG (1969) Bone findings in chronic granulomatous disease of childhood. J Bone Joint Surg (Am) 51: 1573

    Google Scholar 

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Authors and Affiliations

  1. Department of Radiology, University of Michigan Medical Center, Box 13, 48 109, Ann Arbor, Michigan, USA

    D. D. Stricof, G. M. Glazer & M. A. Amendola

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  1. D. D. Stricof
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  2. G. M. Glazer
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  3. M. A. Amendola
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Stricof, D.D., Glazer, G.M. & Amendola, M.A. Chronic granulomatous disease: value of the newer imaging modalities. Pediatr Radiol 14, 328–331 (1984). https://doi.org/10.1007/BF01601886

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