Unusual CNS presentation of neuroblastoma
Neuroblastoma is a common tumor of childhood, usually occurring in children under 4 years of age . We report a case of a 10-year old child who initially presented with a large calvarial mass representing a solitary site of metastasis from an occult adrenal neuroblastoma. The “sunburst” pattern of the calvarial metastasis noted in this case is rarely seen with neuroblastoma. The age of our patient, solitary focus of metastasis at presentation, and imaging appearance of the tumor are very uncommon findings of neuroblastoma.
KeywordsPublic Health Neuroblastoma Common Tumor Imaging Appearance Uncommon Finding
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
Bousvarous A, Kirks DR, Grossman H (1986) Imaging of neuroblastoma: an overview. Pediatr Radiol 16:89–106PubMedGoogle Scholar
Woods WG, Lemieux B, Tuchman M (1992) Neuroblastoma represents distinct clinical-biologic entities: a review and perspective from the Quebec Neuroblastoma Screening Project. Pediatrics 89:114–118PubMedGoogle Scholar
Shaw PJ, Eden T (1992) Neuroblastoma with intracranial involvement: an ENSG study. Med Pediatr Oncol 20:149–155PubMedGoogle Scholar
David R, Lamki N, Fan S, Singleton EB, Eftekhari F, Shirkhoda A, et al (1989) The many faces of neuroblastoma. Radiographics 9:859–882PubMedGoogle Scholar
Haddad A, Azouz M, Al-Jedher S, Baruchel S, Bernstein ML, Cotton RT (1992) Metastatic neuroblastoma presenting as a mandibular mass. Can Assoc Radiol J 43:436–440PubMedGoogle Scholar
Sener RN (1993) CT of diffuse leptomeningeal metastasis from primary extracerebral neuroblastoma. Pediatr Radiol 23:402–403PubMedGoogle Scholar
Zimmerman RA, Bilaniuk LT (1980) CT of primary and secondary craniocerebral neuroblastoma. AJR 135:1239–1242PubMedGoogle Scholar
De La Monte M, Moore GW Hutchins GM (1983) Nonrandom distribution of metastases in neuroblastic tumors. Cancer 52:915–925PubMedGoogle Scholar
Harwood-Nash DC, Fitz CR (1976) Neuroradiology in infants and children. Mosby, Saint Louis, p 136Google Scholar
Pascual-Castroviejo, Lopez-Martin V, Rodriguez-Costa T, Pascual-Pascual JI (1975) Radiological and anatomical aspects of the cranial metastases of neuroblastomas. Neuroradiology 9:33–38Google Scholar