Pediatric Radiology

, Volume 26, Issue 1, pp 19–21 | Cite as

Radiologic-Pathologic Conference of Children's Hospital Boston: New pulmonary nodules in a child undergoing treatment for a solid malignancy

  • M. P. D'Alessandro
  • H. P. W. Kozakewich
  • K. R. Cooke
  • G. A. Taylor


The appearance of pulmonary nodules in a child with a solid malignancy undergoing chemotherapy is a clinically worrisome event. The diagnosis in such cases is not always metastatic disease, and the differential diagnosis should include granulomatous disease, atelectasis, pneumonia, inflammatory pseudotumor, hamartoma, radiation pneumonitis, and bronchiolitis obliterans with organizing pneumonia. There is no consistent radiologic feature to help distinguish benign from malignant causes of these new lesions. However, repeat chest CT 4–6 weeks after the lesions are first noted can be used to track lesion progression and may obviate the need for biopsy.


Public Health Radiation Nodule Pneumonia Differential Diagnosis 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer-Verlag 1996

Authors and Affiliations

  • M. P. D'Alessandro
    • 1
  • H. P. W. Kozakewich
    • 2
  • K. R. Cooke
    • 3
  • G. A. Taylor
    • 1
  1. 1.Department of RadiologyChildren's Hospital and Harvard Medical SchoolBostonUSA
  2. 2.Department of PathologyChildren's Hospital and Harvard Medical SchoolBostonUSA
  3. 3.Department of Pediatric OncologyDana Faber Cancer CenterBostonUSA

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