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Unusual amino acids VIII. Asymmetric hydrogenation of some heteroaryl-N-CBZ and N-BOC aminocinnamic acid derivatives

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Summary

(Z)-α-[(Benzyloxy)- or (tert.-butyloxy)carbonylamino]-β (thienyl)-or (furyl)-acrylic acids and their esters were prepared by known methods and hydrogenated to the corresponding optically active alanine derivatives with optical yields in the range of 58–93% ee using the cationic rhodium complex of “PROPRAPHOS”.

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References

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Authors and Affiliations

  1. Institut für Organische Katalyseforschung an der Universität Rostock e.V., Buchbinderstraße 5-6, D-18055, Rostock, Germany

    H. -J. Kreuzfeld, M. Michalik &  Chr Döbler

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  1. H. -J. Kreuzfeld
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  2. M. Michalik
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  3. Chr Döbler
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Kreuzfeld, H.J., Michalik, M. & Döbler, C. Unusual amino acids VIII. Asymmetric hydrogenation of some heteroaryl-N-CBZ and N-BOC aminocinnamic acid derivatives. Amino Acids 16, 21–27 (1999). https://doi.org/10.1007/BF01318882

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  • DOI: https://doi.org/10.1007/BF01318882

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