Skip to main content
SpringerLink
Log in

Aneuploidy in spermatozoa using fluorescence in situ hybridization

  • News and Views
  • Genetics
  • Published:
Journal of Assisted Reproduction and Genetics Aims and scope Submit manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

References

  1. Pearson PL, Bobrow M, Vosa CG: Technique for identifying Y chromosomes in human interphase nuclei. Nature 1970;226:78

    Google Scholar 

  2. Caspersson T, Zech L, Johannson C, Modest EJ: Identification of human chromosomes by DNA binding fluorescent agents. Chromosoma 1970;30:215

    Google Scholar 

  3. Barlow P, Vosa CG: The Y chromosome in human spermatozoa. Nature 1970;226:961

    Google Scholar 

  4. Wryobeck AJ, Gordon L, Burkhart J, Francis M, Kapp R Jr, Letz G, Malling H, Topham J, Whorton M: An evaluation of human sperm as indicators of chemically induced alterations of spermatogenic function. A report of the U.S. Environmental Protection Agency Gene-tox Program. Mutat Res 1983;115:73

    Google Scholar 

  5. Roberts AM, Goodall H: Y chromosome visibility in Quinacrine stained spermatozoa. Nature 1976;262:493

    Google Scholar 

  6. Sumner AT, Robinson JA: A difference in the dry mass between the heads of the X and Y bearing spermatozoa. J Reprod Fertil 1976;48:9

    Google Scholar 

  7. Pawlowitzki IH, Pearson PL: Chromosomal aneuploidy in human spermatozoa. Humangenetik 1972;46:119

    Google Scholar 

  8. Beatty RA: F-bodies as chromosome markers in mature human sperm heads. Cytogenet Cell Genet 1977;18:33

    Google Scholar 

  9. Rudak E, Jacobs PA, Yanagimachi R: Direct analysis of the chromosome constitution of human spermatozoa. Nature 1978;274:911

    Google Scholar 

  10. Brandriff B, Gordon L, Ashworth L, Watchmaker G, Carrano AV, Wryobeck AJ: Chromosomal abnormalities in human sperm: Comparisons among four healthy men. Hum Genet 1984;66:193

    Google Scholar 

  11. Brandriff B, Gordon L, Ashworth L, Watchmaker G, Moore II D, Wryobeck AJ, Carrano AV: Chromosomes of human sperm: Variability among normal individuals. Hum Genet 1985;70:18

    Google Scholar 

  12. Martin RH, Lin CC, Balkan W, Burns K: Direct chromosomal analysis of human spermatozoa: Preliminary results from 18 normal men. Am J Hum Genet 1982;34:459

    Google Scholar 

  13. Martin RH, Balkan W, Burns K, Rademaker AW, Lin CC, Rudd NL: The chromosome constitution of 1000 human spermatozoa. Hum Genet 1983;63;605

    Google Scholar 

  14. Martin RH, Rademaker AW, Hildebrand K, Long-Simpson L, Peterson D, Yamamoto J: Variation in the frequency and type of sperm chromosomal abnormalities among normal men. Hum Genet 1987;77:108

    Google Scholar 

  15. Martin RH, Rademaker AW: The frequency of aneuploidy among individual chromosomes in 6,821 human sperm chromosome complements. Cytogenet Cell Genet 1990;53:103

    Google Scholar 

  16. Estop AM, Cieply K, Vankirk V, Munne S, Garver K: Cytogenetic studies in human sperm. Hum Genet 1991;87:447

    Google Scholar 

  17. Genesca A, Benet J, Caballin MR, Germa JR, Egozcue J: Significance of structural chromosome abberations in human sperm: Analysis of induced abberations. Hum Genet 1990;85:495–499

    Google Scholar 

  18. Alikani M, Adler A, Reing A, Malter H, Cohen J: Subzonal sperm insertion and the frequency of gamete fusion. J Assist Reprod Genet 1992;9:97

    Google Scholar 

  19. Joseph AM, Gosden JR, Chandley AC: Estimation of aneuploidy levels in human spermatozoa using chromosome specific probes and in situ hybridization. Hum Genet 1984;66:234

    Google Scholar 

  20. Wryobeck AJ, Alhborn T, Balhorn R, Stanker L, Pinkel D: Fluorescence in situ hybridization to Y chromosomes in decondensed human sperm nuclei. Mol Reprod Dev 1990;27:1–9

    Google Scholar 

  21. Pieters MHEC, Geraedts JPM, Meyer H, Dumoulin JCM, Evers JLH, Jongbloed RJE, Nederlof PM, van der Flier S: Human gametes and zygotes studied by nonradioactive in situ hybridization. Cytogenet Cell Genet 1990;53:15

    Google Scholar 

  22. Guttenbach M, Schmid M: Determination of Y chromosomal aneuploidy in human sperm nuclei by nonradioactive in situ hybridization. Am J Hum Genet 1990;46:553

    Google Scholar 

  23. Han TL, Ford JH, Webb GC, Flaherty SP, Correll A, Mathews CD: Simultaneous detection of X and Y bearing human sperm by double fluorescence in situ hybridization. Mol Reprod Dev 1993;34:308

    Google Scholar 

  24. Jacobs PA, Browne C, Gregson N et al: Estimates of the frequency of chromosome abnormalities detectable in unselected newborns using moderate levels of banding. J Med Genet 1992;29(2):103–108

    Google Scholar 

  25. Jacobs PA: Chromosome abnormalities and fertility in man.In Proceedings International Symposium, the Genetics of Spermatozoon, Edinburgh, Beatty RA, Gluecksohn-Waelsch S (eds). 1971, pp 346–358

Download references

Author information

Authors and Affiliations

  1. The Gamete and Embryo Research Laboratory, The Center for Reproductive Medicine and Infertility, Cornell University Medical Center, 505 East 70th Street, HT 305, 10021, New York, New York, USA

    G. L. Schattman, S. Munné, J. G. Grifo, L. Carton & J. Cohen

Authors
  1. G. L. Schattman
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. S. Munné
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. J. G. Grifo
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. L. Carton
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. J. Cohen
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Schattman, G.L., Munné, S., Grifo, J.G. et al. Aneuploidy in spermatozoa using fluorescence in situ hybridization. J Assist Reprod Genet 10, 360–365 (1993). https://doi.org/10.1007/BF01213431

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF01213431

Search

Navigation