Abstract
Our in vitro fertilization (IVF) program provides a unique opportunity to evaluate influences of hormonal milieu on pregnancy outcome, by using a shared pool of oocytes obtained by donors (in exchange for financial assistance). The study presented herein evaluated 38 retrieval cycles (28 oocyte donors/22 recipients). No difference in mean number of embryos transferred was seen (2.7 in the donors vs 2.8 in the recipients). However, a statistically significant difference was seen in the pregnancy rates per retrieval (10.5% donors vs 29% recipients) and per transfer (4/35, 11.1%, vs 11/34, 32.3%). Abortion rates were similar (25% donor, 27.2% recipients). These data suggest that other reports of higher pregnancy rates from donor oocyte programs may not be due exclusively to better-quality oocytes. Possibly a negative effect of hyperstimulation or adverse endometrial environment of the donor (possible chronic endometritis) may explain these data.
Similar content being viewed by others
References
Blankstein J, Quigley MM, Schover LR, Reis J, Kanoti G, Collins RL: Oocyte donation using matched, anonymous donors: Donor selection and screening.In Proceedings of the 45th Annual Meeting of the American Fertility Society, 1989 Abstracts of the Scientific Paper and Poster Sessions, Abstract p-201 (Poster Session—Clinical Assisted Reproductive Technology)
Devroey P, Smith J, Camus M, Wisanto A, Deschacht J, Van Waesberghe L, Van Steirteghem AC: Synchronization of donor's and recipient's cycles with GnRH analogues in an oocyte donation program. Hum Reprod 1989;4(3):270–274
Ben-Nun I, Ghetler Y, Gruber A, Jaffe R, Fejgin M: Egg donation in an in vitro fertilization program: An alternative approach to cycle synchronization and timing of embryo transfer. Fertil Steril 1989;52:683–687
Borrero C, Remohi J, Ord T, Balmaceda JP, Rojas F, Asch RH: A program of oocyte donation and gamete intra-fallopian transfer. Hum Reprod 1989;4(3):275–279
Meldrum DR, Wisot A, Hamilton F, Gutlay AL, Kempton W, Huynh D: Routine pituitary suppression with leuprolide before ovarian stimulation for oocyte retrieval. Fertil Steril 1989;51:455–459
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Check, J.H., Nowroozi, K., Chase, J. et al. Comparison of pregnancy rates following in vitro fertilization—embryo transfer between the donors and the recipients in a donor oocyte program. J Assist Reprod Genet 9, 248–250 (1992). https://doi.org/10.1007/BF01203822
Issue Date:
DOI: https://doi.org/10.1007/BF01203822