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Adamantylazoles. Acid-catalyzed adamantylation of 1,2,4-triazoles

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Chemistry of Heterocyclic Compounds Aims and scope

Abstract

The reaction of 1-adamantanol with 1,2,4-triazole in sulfuric acid forms 1-adamantyl derivatives. In boiling chloroform containing traces of sulfuric acid, a mixture of isomeric N-adamantyl-1, 2, 4-triazoles is obtained. It is shown that 1-adamantyl carbocation is formed at a sulfuric acid concentration above 70%.

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Authors
  1. V. V. Saraev
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  2. T. P. Kanakina
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  3. M. S. Pevzner
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  4. E. L. Golod
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  5. B. I. Ugrak
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  6. V. V. Kachala
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Additional information

St. Petersburg State Technological Institute, St. Petersburg 198013. N. D. Zelinskii Institute of Organic Chemistry, Russian Academy of Sciences, Moscow 117913. Translated from Khimiya Geterotsklicheskii Soedinenii, No. 8, pp. 1078–1087, August, 1996. Original article submitted June 7, 1996.

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Saraev, V.V., Kanakina, T.P., Pevzner, M.S. et al. Adamantylazoles. Acid-catalyzed adamantylation of 1,2,4-triazoles. Chem Heterocycl Compd 32, 928–936 (1996). https://doi.org/10.1007/BF01176969

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