Abstract
4-Phenyl- and 4-methylthiazolylhydrazones were brominated in chloroform and acetic acid. The use of 1.5 equivalents of bromine led to the exclusive formation of the 5-halo derivatives. Effects of substituents on the thiazole ring and of the hydrazone fragment aromatic ring on the course of the reaction were discovered.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
S. V. Usol'tseva, G. P. Andronnikova, and V, A. Sevyrin, Khim. Geterotsikl. Soedin., No. 2, 257 (1993).
G. P. Andronnikova, A. B. Denisova, S. V. Usol'tseva, and A. T. Lebedev, Zh. Org. Khim.,28, 2623 (1992),
S. V. Usol'tseva and G. P. Andronnikova, Abstracts of the All-Union Conference on the Chemistry of Nitrogen Heterocycles [in Russian], Part 2, Chernogolovka (1991), p. 172.
S. V. Usol'tseva, G. P. Andronnikova, and S. L. Nikolaeva, Zh. Org. Khim.,27, 2445 (1991).
Additional information
Urals State Technical University-UPI, 620002 Yekaterinburg. Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 7, pp. 991–995, July, 1995. Original article submitted March 1, 1995.
Rights and permissions
About this article
Cite this article
Denisova, A.B., Andronnikova, G.P. Bromination of 4-substituted thiazolylhydrazones. Chem Heterocycl Compd 31, 863–867 (1995). https://doi.org/10.1007/BF01170750
Issue Date:
DOI: https://doi.org/10.1007/BF01170750