Abstract
The corresponding NN-dimethyl-N′-(thieno[2,3-b]pyrimidin-S-yl)formamidines and S-acylaminothieno[2,3d]pyrimidines have been synthesized by the reaction of ethyl 5-amino-2-substituted thieno[2, 3-d]pyrimidine-6carboxylates with (a) either the dimethylacetal of dimethylfortnamide or chloroacetyl chloride or (b) ethoxycarbonylacetyl chloride or acetic anhydride. Heating ethyl S-amino-2-methylthiothieno[2, 3-d]pyrimidine6-carboxylate with allyl isothiocyanate in pyridine gave 3-allyl-2-allylthio-7-methylthiotlzieno[2, 3-d:4, 5d′]pyrimidin-4(3H)-one.
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Vilnius University, Vilnius 2006, Lithuania. Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 7, pp. 986–990, July, 1995. Original article submitted May 19, 1995.
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Tumkyavichius, S. Synthesis of substituted 5-aminothieno[2,3d] pyrimidines. Chem Heterocycl Compd 31, 859–862 (1995). https://doi.org/10.1007/BF01170749
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DOI: https://doi.org/10.1007/BF01170749