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Chemistry of Heterocyclic Compounds

, Volume 32, Issue 3, pp 359–364 | Cite as

2-Bromo-i-phenylethylidenemalononitrile in the synthesis of thieno[3,2-b]pyridines and thiazolo[4,5-b]pyridines

  • V. L. Ivanov
  • V. A. Artemov
  • A. M. Shestopalov
  • V. N. Nesterov
  • Yu. T. Struchkov
  • V. P. Litvinov
Article
  • 29 Downloads

Abstract

A novel regioselective synthesis of thieno[3, 2-blpyridines and thiazolo[4,5-blpyridines from 2-bromo-I-phenyl ethylidenemalononitrile is proposed. In the case of the thiazolo[4, 5-b]pyridines, the intermediate 5-(2, 2-dicyano-l-phenylvinyl)thiazoles were separated. Formation of the thiazolo(4,5-b]pyridines was confirmed by x-ray analysis.

Keywords

Organic Chemistry Pyridine Thiazole Regioselective Synthesis 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Plenum Publishing Corporation 1996

Authors and Affiliations

  • V. L. Ivanov
  • V. A. Artemov
  • A. M. Shestopalov
  • V. N. Nesterov
  • Yu. T. Struchkov
  • V. P. Litvinov

There are no affiliations available

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