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Synthesis of adenine derivatives containing an amino alcohol fragment

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Chemistry of Heterocyclic Compounds Aims and scope

Abstract

The alkylation of adenine and N(in6)-substituted adenine derivatives by 1, 2-dihaloethanes and the production of 9-(2-haloethyl)derivatives of adenine were studied. 1n the reaction of the derivatives with amino alcohols a series of adenine derivatives containing an amino alcohol fragment was synthesized.

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References

  1. N. P. Rarnzaeva, Yu. Sh. Goldberg, É. R. Alksnis, M. Yu. Lidak, and M. V. Shimanskaya, Zh. Org. Khim.,25, 1783 (1989).

    Google Scholar 

  2. N. Ramzaeva, Yu. Goldberg, E. Alksnis, and M. Lidaks, Synth. Commun.,19, 1669 (1989).

    Google Scholar 

  3. N. Ramzaeva, Yu. Goldberg, E. Alksnis, and M. Lidaks, Synth. Commun.,19, 3121 (1989).

    Google Scholar 

  4. E. Alksnis, N. Ramzaeva, M. Lidaka, and E. Lukevics, International Conference on Environmental and Biological Aspects of Main-Group Organometals, Abstracts, Bordeaux (1994), PC8.

  5. L. Fellows, Chem. Brit.,23, 842 (1987).

    Google Scholar 

  6. J. W. Dennis, K. Koch, S. Yuosefi, and I. Van der Elst, Cancer Res.,50, 1867 (1990).

    Google Scholar 

  7. D. T. Browne, J. Eisinger, and N. J. Leonard, J. Am. Chem. Soc.,90, 7302 (1968).

    Google Scholar 

  8. N. P. Ramzaeva, M. Yu. Lidak, Yu. Sh. Gol'dberg, and M. V. Shimanskaya, Khim. Geterotsikl. Soedin., No. 3, 113 (1987).

  9. N. P. Ramzaeva, M. Yu. Lidak, Yu. Sh. Gol'dberg, and M. V. Shimanskaya, Zh. Org. Khim.,24, 1090 (1988).

    Google Scholar 

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Additional information

Latvian Institute of Organic Synthesis, Riga, LV-1006. Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 3, pp. 386–390, March, 1996. Original article submitted March 7, 1995.

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Alksnis, É., Lidak, M. Synthesis of adenine derivatives containing an amino alcohol fragment. Chem Heterocycl Compd 32, 333–337 (1996). https://doi.org/10.1007/BF01169254

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  • DOI: https://doi.org/10.1007/BF01169254

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