Abstract
It is shown that the reaction of tosythydrazones of 3-hydroxypiperidin-4-ones with bases, depending on the nature of the latter, results in a rearrangement with a narrowing of the heterocycle and formation of acetylpyrrolidines, or in the formation of 3-hydroxy-1,2,3,6,-tetrahydropyridines.
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References
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Additional information
Belorussian State Technological University, Minsk, 220030. Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 3. pp. 361–363, March, 1996. Original article submitted June 26, 1995.
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Zvonok, A.M., Okaev, E.B. Shapiro reaction in the series of piperidine derivatives. Synthesis of 3-hydroxy-1,2,3,6-tetrahydropyridines. Chem Heterocycl Compd 32, 310–312 (1996). https://doi.org/10.1007/BF01169248
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DOI: https://doi.org/10.1007/BF01169248