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Chemistry of Heterocyclic Compounds

, Volume 1, Issue 1, pp 66–68 | Cite as

Synthesizing isomeric methoxy derivatives of 6-nitro-9-chlordacridine and 6-nitroacridone

  • A. K. Sukhomlinov
  • V. P. Maksimets
Article
  • 33 Downloads

Abstract

Condensation of 2-chloro-4-nitrobenzoic acid with o, m, and p-anisidines under the conditions of the Ullmann reaction gives the corresponding 2′-, 3′-, or 4′-methoxy derivatives of 5-nitrodiphenylamine-2-carboxylic acid. Phosphorus oxychloride cyclizes the latter to the corresponding methoxy-substituted 6-nitro-9-chloroacridines, and the latter, when treated with dilute hydrochloric acid, give good yields of methoxy derivatives of 6-nitroacridones.

Keywords

Phosphorus Organic Chemistry Hydrochloric Acid Methoxy Good Yield 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© The Faraday Press, Inc. 1965

Authors and Affiliations

  • A. K. Sukhomlinov
    • 1
  • V. P. Maksimets
    • 1
  1. 1.Kharkov Pharmaceutical InstituteUSSR

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