Chemistry of Heterocyclic Compounds

, Volume 1, Issue 1, pp 57–59 | Cite as

Study of lactams. VI. Synthesis of 6-substituted purino [8, 9-11, 22]isoindol1nes

  • R. G. Glushkov
  • O. Yu. Magidson


It is shown with 1-ethoxyisoindolenine that the reaction of lactim ethers with α-amino-α-cyanoacetamide also extends to partly aromatized lactim ethers, although these react much less readily. Condensation of 1-ethoxyisoindolenine with α-amino-cyanoacetamide gives 4-carbamido-5-aminoimidazo[1, 2-1′, 2′]isoindoline, from which a new series of purinoisoindioline derivatives is synthesized.


Ether Organic Chemistry Lactam Isoindoline Lactim Ether 
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Copyright information

© The Faraday Press, Inc. 1965

Authors and Affiliations

  • R. G. Glushkov
    • 1
  • O. Yu. Magidson
    • 1
  1. 1.Ordzhonikidze All-Union Chemical-Pharmaceutical Scientific Research InstituteMoscow

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