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Synthesis of β-substituted tetrahydrofurans by the prins reaction

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Chemistry of Heterocyclic Compounds Aims and scope

Abstract

Mixtures of 3-trif uoroacetoxy- and 3-chloro-4-alkyltetraliydrofurans were synthesized by the reaction of a series ofα-olefins with formaldehyde in trifuoroacetic acid and trimethylchlorosilane.

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References

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Additional information

The characteristics of the mixtures of cis and trans isomers are given, and the nD 20 values are given for the trans isomers.

Bashkir State University, Institute of Fine Organic Synthesis. Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 5, pp. 605–608, May, 1995. Original article submitted November 4, 1994; revision submitted May 10, 1995.

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Talipov, R.F., Muslukhov, R.R., Safarov, I.M. et al. Synthesis of β-substituted tetrahydrofurans by the prins reaction. Chem Heterocycl Compd 31, 530–533 (1995). https://doi.org/10.1007/BF01166323

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  • DOI: https://doi.org/10.1007/BF01166323

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