Advertisement

Chemistry of Heterocyclic Compounds

, Volume 30, Issue 6, pp 709–712 | Cite as

Novel synthesis of 3-aryl-5,6-dihydropyridin-2(1H)-ones

  • A. S. Fisyuk
  • M. A. Vorontsova
  • S. A. Ivanov
Article

Abstract

Cyclization of N-3-oxoalkylamides of substituted phenylacetic acids under the influence of bases produces 3-aryl-substituted 5, 6-dihydropyridin-2(1H)-ones. Dehydrogenation of these latter compounds yields substituted pyridin-2(1H)-ones.

Keywords

Organic Chemistry Dehydrogenation Phenylacetic Acid Compound Yield 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. 1.
    M. Sekiya and Y. Watarase, Jpn. pat. 54-70283.Google Scholar
  2. 2.
    N. Ohba, A. Ikeda, K. Matsunari, Y. Yamada, M. Hirata, Y. Nakamura, and A. Takeuch, U.S. Pat. 5,006,157.Google Scholar
  3. 3.
    D. O. Imbrosi and N. S. Simpkins, Tetrahedron Lett.,30, 4309 (1989).Google Scholar
  4. 4.
    M. Nakagawa, Z. Lai, Y. Tarisawa, and H. Hito Heterocyeles,31, 999 (1990).Google Scholar
  5. 5.
    M. Shama and P. Rosenstock, J Org. Chem.,26, 718 (1961).Google Scholar
  6. 6.
    M. Komatsu, S. Yamamoto, Y. Oshiro, and T. Agawa, Tetrahedron Lett.,22, 3769 (1981).Google Scholar
  7. 7.
    A. B. Fissiouk M. A. Vorontsova, and R. S. Sagitullin, Mendeleev Commun., 249 (1993).Google Scholar
  8. 8.
    R. R. Schmidt, Chem. Ber.,98, 334 (1965).Google Scholar
  9. 9.
    M. Lora-Tamayo, R. Madronero, G. Garcia Munos, and H. Leipprand, Chem. Ber.,97, 2234 (1964).Google Scholar
  10. 10.
    K. Ikeda, Y. Terao, and M. Sekiya, Chem. Pharm. Bull.,29, 1156 (1981).Google Scholar
  11. 11.
    A. V. Shastin and E. S. Balenkova, Zh. Org. Khim.,20, 1357 (1984).Google Scholar
  12. 12.
    G. N. Walker, J. Am. Chem. Soc.,77, 3844 (1955).Google Scholar

Copyright information

© Plenum Publishing Corporation 1995

Authors and Affiliations

  • A. S. Fisyuk
  • M. A. Vorontsova
  • S. A. Ivanov

There are no affiliations available

Personalised recommendations