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Chemistry of Heterocyclic Compounds

, Volume 32, Issue 2, pp 206–209 | Cite as

Reaction of 3-cyanopyridine-2(1H)-thiones with N-butyllithium

  • N. G. Frolova
  • V. K. Zav'yalova
  • V. P. Litvinov
Article
  • 54 Downloads

Abstract

The reaction of 3-cyanopyridine-2(1 H)-thiones with BuLi in ether was studied. It was found that the metallation proceeds initially at the sulfur atom. The resulting lithium salts add a second equivalent of n-butyllithium at the CN group. The hydrolysis of the dilithium derivatives leads to 3 pentanoylpyridine-2(IH)-thiones.

Keywords

Sulfur Ether Hydrolysis Lithium Organic Chemistry 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Plenum Publishing Corporation 1996

Authors and Affiliations

  • N. G. Frolova
    • 1
  • V. K. Zav'yalova
    • 1
  • V. P. Litvinov
    • 1
  1. 1.N. D. Zelinskii Institute of Organic ChemistryRussian Academy of Sciences (RAN)Moscow

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