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Chemistry of Heterocyclic Compounds

, Volume 32, Issue 2, pp 163–168 | Cite as

Recyclization of 2-imino-2h-1-benzopyrans under the influence of nucleophilic reagents. 1. New approach to the synthesis of 3-(1,3,4oxadi-, thiadi-, and triazolyl-2)coumarins

  • S. N. Kovalenko
  • V. A. Zubkov
  • V. P. Chernykh
  • A. V. Turov
  • S. M. Ivkov
Article

Abstract

It has been found that under the action of hydrazides of carboxylic acids, 2-iminocoumarin-3-carboxamides are recyclized to N(1)-acylamidrazones of coumarin-3-carboxylic acids. The use of N(1)-acylamidrazones is proposed as a simple and effective means of synthesizing 3-(1,3,4-oxadi-, thiodi-, and triazolyl-2)coumarins. The possibilities of alternate schemes of synthesis are discussed, and a mechanism is suggested for the recyclization.

Keywords

Organic Chemistry Carboxylic Acid Coumarin Alternate Scheme Hydrazide 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Plenum Publishing Corporation 1996

Authors and Affiliations

  • S. N. Kovalenko
    • 1
  • V. A. Zubkov
    • 1
  • V. P. Chernykh
    • 1
  • A. V. Turov
    • 1
  • S. M. Ivkov
    • 1
  1. 1.krainian Pharmaceutical AcademyKhar'kov

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