Abstract
In a solution of DMF, 2-carbethoxymethyl-4H-3,1-benzoxazin-4-one reacts with primarily aromatic amines basically with the formation of the corresponding 2-carbethoxymetlzyl-3-arylquinazolin-4(3H)-ones. Possible mechanisms of these chemical transformations are reported and discussed.
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1. V. Ukrainets, P. A. Bezuglyi, V. 1. Treskach, and A. V. Turov, Khim. Geterotsikl. Soedin., No. 2, 239 (1992).
P. A. Petyunin, V. P. Chernykh, G. P. Petyunin, and Yu. V. Kozhevnikov, Khim. Geterotsikl. Soedin., No. 11, 1575 (1970).
L. A. Errede, J. Org. Chem.,41, 1763 (1976).
L. A. Errede, J. J. McBrady, and H. T. Oien, J. Org. Chem.,41, 1765 (1976).
R. V. Poponova, B. M. Bolotin, L. S. Zeryukina, and R. U. Safina, Khim. Geterotsikl. Soedin., No. 5, 614 (1977).
P. A. Petyunin and Yu. V. Kozhevnikov, Zh. Obshch. Khim.,30, 2352 (1960).
P. A. Petyunin and Yu. V. Kozhevnikov, Zh. Obshch. Khim.,34, 854 (1964).
P. A. Bezuglyi, l. V. Ukrainets, V. I. Treskach, and V. A. Georgiyants, Khar'kov State Pharmaceutical Institute, Khar'kov (1989); submitted to UkrNIINTI, No. 2066-Uk 89 (09.21.89).
S. Malhotra, S. K. Koul, S. Singh, G. B. Singh, and K. L. Dhar, Ind. J. Chem.,28B, 100 (1989).
U. I. Sabagh, H. H. Hassanein, and M. I. Ashmawi, Egypt. J. Pharm. Sci.,29, 595 (1988).
J. F. Wolfe, T. L. Rathman, M. C. Sleevi, J. A. Campbell, and T. D. Greenwood, J. Med. Chem.,33, 161 (1990).
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Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 2, pp. 225–228, February, 1994. Original article submitted June 28, 1993.
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Ukrainets, I.V., Taran, S.G., Gorokhova, O.V. et al. 2-Carbethoxymethyl-4H-3,1-benzoxazin-4-one. 4. Reaction with anilines. Chem Heterocycl Compd 30, 204–207 (1994). https://doi.org/10.1007/BF01165013
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DOI: https://doi.org/10.1007/BF01165013