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Reaction of 1-chloro-1-aryl2,2,2-trifluoroethylisocyanates with the ethyl ester ofβ-N-methylaminocrotonic acid. Synthesis of 2-aryl-2-trifluoromethyl-1,2,3,4-tetrahydropyrimidin-4-ones

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Abstract

1-Chloro-l-aryl-2, 2, 2-trifluoroethylisocyanates react with the ethyl ester of β-N-methylaminocrotonic acid with formation of derivatives of 1,2,3,4-tetrahydropyrimidin-4-ones.

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Authors and Affiliations

  1. Institute of Organic Chemistry, Academy of Sciences of Ukraine, 252660, Kiev

    M. V. Vovk & V. V. Pirozhenko

Authors
  1. M. V. Vovk
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  2. V. V. Pirozhenko
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Translated from Khimiya Geterotsiklicheskikh Soedinenii, Vol. 30, No. 1, pp. 96–98, January, 1994.

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Vovk, M.V., Pirozhenko, V.V. Reaction of 1-chloro-1-aryl2,2,2-trifluoroethylisocyanates with the ethyl ester ofβ-N-methylaminocrotonic acid. Synthesis of 2-aryl-2-trifluoromethyl-1,2,3,4-tetrahydropyrimidin-4-ones. Chem Heterocycl Compd 30, 85–87 (1994). https://doi.org/10.1007/BF01164740

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  • DOI: https://doi.org/10.1007/BF01164740

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