Chemistry of Heterocyclic Compounds

, Volume 32, Issue 9, pp 1095–1099 | Cite as

Reactions of 2-aminobenzothiazoles with ethylene chlorohydrin. molecular and crystal structure of bis[(3-β-hydroxyethyl)benzo-thiazolyl-2-indene]ammonium chloride

  • M. K. Makhmudov
  • R. F. Ambartsumova
  • B. Tashkhodzhaev


Hydroxyethylation of 2-aminobenzothiazoles by ethylene chlorohydrin unexpectedly led to preferential formation of 3-β-chloroethylbenzothiazolin-2-one. In the case of unsubstituted 2-aminobenzothiazole, we also isolated the target 2-indno-3-β-hydroxyethylbenzothiazoline and bis((3-/3-hydroxyethyl)benzothiazolyl-2-indenelamnionium chloride. As a result of reaction of 2-aminobenzothiazole with 3-β-chloroethylbenzothiazolin-2-one, we obtained 2-(benzothiazolyl-2-imino)-3-(β-(2-oxobenzothiazolin-3-yl)ethyllbenzothiazoline. The structure ofthesynthesized compounds was established based on x-ray diffraction, PMR, IR, UV, and mass spectra.


Ethylene Chloride Ammonium Crystal Structure Mass Spectrum 
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Copyright information

© Plenum Publishing Corporation 1997

Authors and Affiliations

  • M. K. Makhmudov
  • R. F. Ambartsumova
  • B. Tashkhodzhaev

There are no affiliations available

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