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Chemistry of Heterocyclic Compounds

, Volume 32, Issue 9, pp 1078–1083 | Cite as

Alkyl derivatives of 1-aryldihydro-4(IH,3H)-pyrimidinone-2-thiones and their structure

  • V. Yu. Mitskyavichyus
  • I. Ch. Bilinskaite
Article
  • 42 Downloads

Abstract

The alkylation of 1-aryldihydro-4(IH,3H)-pyrimidinone-2-thiones goes through both at the thiol group and at the amide nitrogen atom of the heterocycle. Enlargement of the alkyl radical favors an increase in the portion of the N-alkyl derivative in the mixture. The influence of the folding of the heterocycle on its barrier to rotation around the Ph-N1 bond was shown.

Keywords

Nitrogen Organic Chemistry Amide Thiol Nitrogen Atom 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

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Copyright information

© Plenum Publishing Corporation 1997

Authors and Affiliations

  • V. Yu. Mitskyavichyus
  • I. Ch. Bilinskaite

There are no affiliations available

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