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Chemistry of Heterocyclic Compounds

, Volume 32, Issue 9, pp 1055–1057 | Cite as

Synthesis and alkylation of 6-methyl-5-phenylcarbamoyl-3-cyano-4-ethylpyridine-2(1H)thione

  • V. D. Dyachenko
  • S. G. Krivokolysko
  • V. P. Litvinov
Article

Abstract

By condensation of the anilide of acetoacetic acid, propionaldehyde, and cyanothioacetamide, 6-methyl-5-phenylcarbamoyl-3-cyano-4-ethylpyridine-2(IH)thione has been obtained. In an alkaline medium, this compound is alkylated, forming the corresponding substituted 2-pyridyl sulfides. From these pyridines, substituted thienoj2,3-blpyridines have been synthesized through the Thorpe-Ziegler reaction.

Keywords

Sulfide Organic Chemistry Propionaldehyde Pyridine Alkylation 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Plenum Publishing Corporation 1997

Authors and Affiliations

  • V. D. Dyachenko
  • S. G. Krivokolysko
  • V. P. Litvinov

There are no affiliations available

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