Abstract
A fertile woman suffering from mild dystrophia myotonica had undergone sterilization because of the 50% genetic risk of this disease developing in her offspring. In her second treatment cycle on the donor oocyte program, four anonymously donated oocytes were inseminated with frozen-thawed sperm of her husband. Three embryos were obtained and two surviving embryos were deep-frozen at the eight-cell stage and kept in storage for 9 months. These embryos were successfully thawed and transferred to the recipient 97 hr after the onset of her luteinizing hormone surge. A normal singleton pregnancy developed and a healthy male infant was delivered by cesarean section at 36 weeks of gestation.
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Trounson A, Leeton J, Besanko M, Wood C, Conti A: Pregnancy established in an infertile patient after the transfer of a donated embryo fertilized in vitro. Br Med J 1983; 286:835–837
Lutjen P, Trounson A, Leeton J, Findlay J, Wood C, Renou P: The establishment and maintenance of pregnancy using in vitro fertilization and embryo donation in a patient with primary ovarian failure. Nature 1984; 307:174–176
Leeton J: Egg and embryo transfer.In In Vitro Fertilization and Donor Insemination, W Thompson, D Joyce, J Newton (eds). Proceedings of the Twelfth Study Group of the Royal College of Obstetricians and Gynaecologists, 1985, pp 285–293
Trounson A, Mohr L: Human pregnancy following cryopreservation, thawing and transfer of an 8-cell embryo. Nature 1983; 305:707–709
McIntosh JEA, Matthews CD, Crocker JM, Broom TJ, Cox LW: Predicting the luteinizing hormone surge: Relationship between the follicular and luteal phases and the length of the human menstrual cycle. Fertil Steril 1980; 34:125–130
Mahadevan M, Trounson A, Leeton J: Successful use of human semen cryobanking for in vitro fertilization. Fertil Steril 1983; 40:340–343
Trounson AO: Manipulation of endocrine requirements for in vitro fertilization. Proc Endocrine Soc Austral 1982; 25(Suppl 1):1–6
Freemann L, Trounson A, Kirby C: Cryopreservation of human embryos: Progress on the clinical use of the technique in human in vitro fertilization. J Vitro Fert Embryo Transfer 1986; 3:53–61
Leeton J, Trounson A, Jessup D, Wood C: The technique for human embryo transfer. Fertil Steril 1982; 38(2): 156–161
Leeton J, Harman J: Attitudes toward egg donation of thirty-four infertile women who donated during their in vitro fertilization treatment. J Vitro Fert Embryo Transfer 1986; 3:374–378
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Leeton, J., Freemann, L., King, C. et al. Successful pregnancy in an ovulating recipient following the transfer of two frozen-thawed embryos obtained from anonymously donated oocytes. J Assist Reprod Genet 5, 22–24 (1988). https://doi.org/10.1007/BF01138865
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DOI: https://doi.org/10.1007/BF01138865