Abstract
An 18-month survey of infertility treatment by in vitro fertilization (IVF) and related procedures at the Centre for Reproductive Medicine of the Vrije Universiteit Brussel is described. During this period, 1326 treatment cycles were started in patients with long-standing infertility and 1135 oocyte retrievals were performed in 771 different patients. IVF and embryo transfer (ET) after laparoscopic (N=793) or ultrasonically guided (N=342) ovum pickup, gamete intrafallopian transfer (GIFT;N=284), or zygote intrafallopian transfer (ZIFT;N=15) combined with IVF as well as the replacement of cryopreserved embryos yielded an overall pregnancy rate of 21.8% per started cycle. Echographic and laparoscopic oocyte retrieval gave similar results except for a higher fertilization rate after echographic-guided retrieval. For in vitro fertilization and embryo transfer an overall pregnancy rate of 26% per transfer was obtained. For GIFT and ZIFT the pregnancy rates were, respectively, 27.8 and 46.7% per replacement. For each procedure onethird of the pregnancies aborted. After the replacement of frozen and thawed embryos, during a natural cycle, a significantly lower fetal loss was observed.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
Van Steirteghem AC, Devroey P, Heip J, Liebaers I, Liu Y, Naaktgeboren N, Olbrechts H, Temmerman M, Verhoeven N: Monitoring of patients in an in vitro fertilization and embryo transfer programme.In Human in Vitro Fertilization and Early Embryo Development, S Bettocci, L Carenza, G Loverro, G Sadurny (eds). Rome, CIC Editione Internationale, f.r.l., 1984, pp 187–200
Devroey P, Wisanto A, Smitz J, Braeckmans P, Van Waesberghe L, Van Steirteghem AC: Ovarian stimulation, including in vitro fertilization. Ann Biol Clin 1987;45:346–350
Braeckmans P, Devroey P, Camus M, Khan I, Staessen C, Smitz J, Van Waesberghe L, Wisanto A, Van Steirteghem AC: Gamete intra-Fallopian transfer: Evaluation of 100 consecutive attempts. Hum Reprod 1987;2:201–205
Van Steirteghem AC, Van Waesberghe L, Camus M, Deschacht J, Devroey P, Smitz J, Wisanto A: Hormonal monitoring for in vitro fertilization and related procedures. Hum Reprod 1988 (in press)
Smitz J, Devroey P, Breackmans P, Camus M, Khan I, Staessen C, Van Waesberghe L, Wisanto A, Van Steirteghem AC: Management of failed cycles in an IVF/GIFT programme with the combination of the GnRH analogue and HMG. Hum Reprod 1987;2:309–314
Smitz J, Devroey P, Camus M, Deschacht J, Khan I, Staessen C, Van Waesberghe L, Wisanto A, Van Steirteghem AC: The luteal phase and early pregnancy after combined GnRH-agonist/HMG treatment for superovulation in IVF or GIFT. Hum Reprod 1988; 3 (in press)
Wisanto A, Braeckmans P, Camus M, Devroey P, Khan I, Staessen C, Smitz J, Van Waesberghe L, Van Steirteghem AC: Perurethral ultrasound guided ovum pick-up. J Vitro Fert Embryo Transfer 1988 (in press)
Tea NT, Jondet M, Scholler R: A migration-gravity sedimentation method for collecting motile spermatozoa from human semen.In In Vitro Fertilization, Embryo Transfer and Early Pregnancy, RF Harrison, J Bonnar, W Thompson (eds). Lancaster, MTP Press, 1983, p 117
Marrs RP, Saito H, Yee B, Sato F, Brown J: Effect of variation of in vitro culture techniques upon oocyte fertilization and embryo development in human in vitro procedures. Fertil Steril 1984;41:519
Veeck L: Atlas of the Human Oocyte and Conceptus. Baltimore, USA, Williams & Wilkins, 1986
Khan I, Camus M, Deschacht J, Smitz J, Staessen C, Van Waesberghe L, Wisanto A, Devroey P, Van Steirteghem AC: Success rate in gamete intrafallopian transfer using low and high concentrations of washed spermatozoa (submitted for publication)
Van Steirteghem AC, Van Den Abbeel E, Camus M, Van Waesberghe L, Braeckmans P, Khan I, Nijs M, Smitz J, Staessen C, Wisanto A, Devroey P: Cryopreservation of human embryos obtained after gamete intra-fallopian transfer and/or in vitro fertilization. Hum Reprod 1987;2:593–598
Devroey P, Braeckmans P, Smitz J, Van Waesberghe L, Wisanto A, Van Steirteghem A, Heytens L, Camu F: Pregnancy after translaparoscopic zygote intrafallopian transfer on a patient with sperm antibodies. Lancet 1986;1:1329
Deschacht J, Devroey P, Camus M, Khan I, Smitz J, Staessen C, Van Waesberghe L, Wisanto A, Van Steirteghem AC: In-vitro fertilization with husband and donor sperm in patients with previous fertilization failures using husband sperm. Hum Reprod 1988;2:603–606
Quigley MM, Sokoloski JE, Withers DM, Richards SI, Reis MJ: Simultaneous in vitro fertilization and gamete intrafallopian transfer (GIFT). Fertil Steril 1987;47:797–801
Miller JF, Williamson E, Glue J, Gordon YB, Grudzinskas JG, Sykes A: Fetal loss after implantation. Lancet 1980; 2:554–556
Gustavii B: Chorionic biopsy and miscarriage in first trimester. Lancet 1984;1:562
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Staessen, C., Camus, M., Khan, I. et al. An 18-month survey of infertility treatment by in vitro fertilization, gamete and zygote intrafallopian transfer, and replacement of frozen-thawed embryos. J Assist Reprod Genet 6, 22–29 (1989). https://doi.org/10.1007/BF01134577
Received:
Accepted:
Issue Date:
DOI: https://doi.org/10.1007/BF01134577