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In vitro fertilization (IVF)-surrogacy: Application of IVF to women without functional uteri

  • Leon A. Sheean
  • James M. Goldfarb
  • Robert Kiwi
  • Wulf H. Utian
Special Contributions

Abstract

Women with absent or dysfunctional uteri consented to controlled ovarian stimulation, ovum aspiration, in vitro fertilization, and embryo culture. Cleaving preembryos were transferred to recipient (surrogate) women whose menstrual cycles were in approximate synchrony with the ovum donor. None of the embryo recipients received medication. Six cases are described, resulting in one spontaneous loss at 6 weeks, four full-term deliveries, and one ongoing pregnancy. HLA typing demonstrated all babies to be genotypic offspring of the gamete donors.

Key Words

in vitro fertilization (IVF)-surrogacy surrogate host hysterectomy mullerian dysgenesis 

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References

  1. 1.
    Utian WH, Sheean LA, Goldfarb JM, Kiwi R: Successful pregnancy after in vitro fertilization and embryo transfer from an infertile woman to a surrogate. N Engl J Med 1985;313:1351–1352Google Scholar
  2. 2.
    Utian WU, Goldfarb JM, Sheean LA: Implementation of an IVF program. J Vitro Fert Embryo Transfer 1984;1:72–75Google Scholar
  3. 3.
    Rosenwaks Z: Donor eggs: Their application in modern reproductive technologies. Fert Steril 1987;47:895Google Scholar
  4. 4.
    Ahuja KK, Smith W, Tucker M, Craft I: Successful pregnancies form transfer of pronuclear embryos in an outpatient in vitro fertilization program. Fert Steril 1985;44:181Google Scholar
  5. 5.
    Craft I, Djahanbakhch O, McLeod F, Bernard A, Green S, Twigg H, Smith W, Lindsey K, Edmonds K: Human pregnancy following oocyte and sperm transfer to the uterus. Lancet 1982;I:1031Google Scholar

Copyright information

© Plenum Publishing Corporation 1989

Authors and Affiliations

  • Leon A. Sheean
    • 1
  • James M. Goldfarb
    • 1
  • Robert Kiwi
    • 1
  • Wulf H. Utian
    • 1
  1. 1.Department of Obstetrics and GynecologyThe Mt. Sinai Medical Center of Cleveland, Laboratory for in Vitro Fertilization and Embryo TransferCleveland

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