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In vitro fertilization in Norfolk, Virginia, 1980–1983

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Abstract

Three years of progress of the Vital Initiation of Pregnancy (VIP) Program in Norfolk is reported. No conception resulted from 41 oocyte aspirations during spontaneous menstrual cycles in 1980. An average of 3.7 oocytes per cycle, or a 73.5% recovery rate, resulted in 362 human menopausal gonadotropin/human chorionic gonadotropin-induced cycles from January 1981 to March 1983. Forty pecent of the oocytes recovered from these cycles were preovulatory, 35% atretic, and 25% immature. Immature oocytes were often matured in vitro, fertilized, and found to produce pregnancies. A total of 62 pregnancies occurred, which represents a 17 or 23% pregnancy rate, based on laporoscopies or embryo transfers, respectively. There were 11 preclinical and 7 clinical miscarriages. Twenty-nine normal babies have been delivered, including a set of twins. The remainder appears to be normally progressing pregnancies. Polyspermia was observed in 8.8% of the fertilizable oocytes.

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References

  1. Veeck LL, Wortham JE, Witmyer J, Sandow B, Acosta AA, Garcia JE, Jones GS, Jones HW Jr: Maturation and fertilization of morphologically immature human oocytes in a program of in vitro fertilization. Fertil Steril 1983:39:594

    PubMed  Google Scholar 

  2. Garcia JE, Jones GS, Wright GL, Jr: Prediction of the time of ovulation. Fertil Steril 1981:36:308

    PubMed  Google Scholar 

  3. Garcia JE, Jones GS: The use of clomiphene citrate. Fertil Steril 1977;28:707

    PubMed  Google Scholar 

  4. Johnston I, Lopata A, Speir A, Hoult I, Kellow G, duPlesis Y: In vitro fertilization: The challenge of the eighties. Fertil Steril 1981;36:699

    PubMed  Google Scholar 

  5. Garcia JE, Jones GS, Acosta AA, Wright GL Jr: Human menopausal gonadotropin/human chrionic gonadotropin follicular maturation for oocyte aspiration: Phase I, 1981. Fertil Steril 1983;39:167

    PubMed  Google Scholar 

  6. Ferraretti AP, Garcia J, Acosta A, Jones GS: Serum LH during ovulation induction for in vitro fertilization in normally menstruating women. Fertil Steril 1983 (in press)

  7. Garcia JE, Jones GS, Acosta AA, Wright G Jr: Human menopausal gonadotropin for oocyte aspiration: Phase II, 1981. Fertil Steril 1983;39:174

    PubMed  Google Scholar 

  8. Jones HW Jr, Jones GS, Andrews MC, Acosta AA, Garcia JE, Sandow B, Veeck LL, Wilkes C, Witmyer J, Wortham JE, Wright G Jr: The program for in vitro fertilization at Norfolk. Fertil Steril 1982;38:14

    PubMed  Google Scholar 

  9. Jones HW Jr, Acosta AA, Garcia JE: A technique for the aspiration of oocytes from human ovarian follicles. Fertil Steril 1982;37:26

    PubMed  Google Scholar 

  10. Wortham JE, Veeck LL, Witmyer J, Jones HW Jr: Vital initiation of pregnancy (VIP) using human menopausal gonadotropin/human chorionic gonadotropin ovulation induction: Phase I, 1981. Fertil Steril 1983;39:785

    PubMed  Google Scholar 

  11. Wortham JE, Veeck LL, Witmyer J, Sandow BA Jones HW Jr: Vital initiation of pregnancy using human menopausal gonadotropin/human chorionic ovulation induction: Phase II, 1981. Fertil Steril 1983;39:241

    PubMed  Google Scholar 

  12. Jones HW Jr, Acosta AA, Garcia JE, Sandow BA, Veeck LL: On the transfer of conceptuses from oocytes fertilized in vitro. Fertil Steril 1983;39:241

    PubMed  Google Scholar 

  13. Garcia JE, Jones GS, Acosta A, Wright G Jr: Corpus luteum function after follicle aspiration for oocyte retrieval. Fertil Steril 1981;36:565

    PubMed  Google Scholar 

  14. Jones GS, Garcia JE, Acosta AA: Luteal phase in in vitro fertilization.In Human Conception in Vitro, Edwards Purdy (eds). London, Academic Press, 1982, p 297

    Google Scholar 

  15. Acosta AA, Garcia JE, Jones GS, Wright GL: Corpus luteum function in patients with hMG/hCG induced ovulation for in vitro fertilization. 1983 (submitted for publication)

  16. Jones HW Jr, Acosta AA, Andrews MC, Garcia JE, Jones GS, Mantzavinos T, Whibley TW, Wilkes CA, Wright GE Jr: What is a pregnancy? A question for programs of in vitro fertilization. Fertil Steril 1983 (in press)

  17. Jones HW Jr, Acosta AA, Andrews MC, Garcia JE, Jones GS, Mantzavinos T, McDowell J, Sandow B, Veeck LL Whibley T, Wilkes C, Wright G Jr: The importance of the follicular phase to success and failure in in vitro fertilization. Fertil Steril 1983 (in press)

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Authors and Affiliations

  1. Department of Obstetrics and Gynecology, Eastern Virginia Medical School, 304 Medical Tower, P.O. Box 1980, 23507, Norfolk, Virginia

    Jairo Garcia

Authors
  1. Jairo Garcia
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  2. Anibal Acosta
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  3. Mason C. Andrews
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  4. Georgeanna Seegar Jones
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  5. Howard W. Jones Jr.
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  6. Themis Mantzavinos
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  7. Jacob Mayer
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  8. Jeanne McDowell
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  9. Bruce Sandow
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  10. Lucinda Veeck
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  11. Theresa Whibley
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  12. Charles Wilkes
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  13. George Wright Jr.
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Garcia, J., Acosta, A., Andrews, M.C. et al. In vitro fertilization in Norfolk, Virginia, 1980–1983. J Assist Reprod Genet 1, 24–28 (1984). https://doi.org/10.1007/BF01129616

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  • DOI: https://doi.org/10.1007/BF01129616

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