Chemistry of Heterocyclic Compounds

, Volume 1, Issue 2, pp 162–164 | Cite as

Phenothiazine syntheses. XVIII. 2-Aminophenothiazine derivatives

  • S. V. Zhuravlev
  • A. N. Gritsenko


2-(α-chloroacetylamido)-2-(β-chloropropionylamido)-2-(benzylideneamino)- and 2-(o-hydroxybenzyllideneamino)phenothiazines are synthesized and reduced by lithium aluminum hydride to 2-ethylamino-, 2-propylamino-, 2-benzylamino-, and 2-(o-hydroxybenzylamino)phenothiazine. Reduction of the methyl and ethyl esters of phenothiazinecarbamic-2 acid by lithium aluminum hydride gives 2-methylaminophenothiazine.


Aluminum Methyl Ester Ethyl Lithium 
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Copyright information

© The Faraday Press, Inc. 1966

Authors and Affiliations

  • S. V. Zhuravlev
    • 1
  • A. N. Gritsenko
    • 1
  1. 1.Institute of Pharmacology and Chemotherapy AMS USSRMoscow

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