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Phenothiazine syntheses. XVIII. 2-Aminophenothiazine derivatives

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Chemistry of Heterocyclic Compounds Aims and scope

Abstract

2-(α-chloroacetylamido)-2-(β-chloropropionylamido)-2-(benzylideneamino)- and 2-(o-hydroxybenzyllideneamino)phenothiazines are synthesized and reduced by lithium aluminum hydride to 2-ethylamino-, 2-propylamino-, 2-benzylamino-, and 2-(o-hydroxybenzylamino)phenothiazine. Reduction of the methyl and ethyl esters of phenothiazinecarbamic-2 acid by lithium aluminum hydride gives 2-methylaminophenothiazine.

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References

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Authors and Affiliations

  1. Institute of Pharmacology and Chemotherapy AMS USSR, Moscow

    S. V. Zhuravlev & A. N. Gritsenko

Authors
  1. S. V. Zhuravlev
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  2. A. N. Gritsenko
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For Part XVII see [1].

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Zhuravlev, S.V., Gritsenko, A.N. Phenothiazine syntheses. XVIII. 2-Aminophenothiazine derivatives. Chem Heterocycl Compd 1, 162–164 (1965). https://doi.org/10.1007/BF01046677

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  • DOI: https://doi.org/10.1007/BF01046677

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