Skip to main content
Log in

Idiopathic infantile arterial calcification: Roentgen diagnosis of a rare cause of coronary artery occlusion

  • Originals
  • Published:
Pediatric Radiology Aims and scope Submit manuscript

Abstract

Infantile arterial calcification is a rare disorder of unknown etiology which is usually generalized and leads to death from coronary artery occlusion. The involved arteries show calcification of the internal elastic lamina and marked intimal proliferation. Vascular calcifications were demonstrated radiographically in 9 previously recorded cases. Three new patients are reported who presented with congestive heart failure. The visualization of faint vascular calcifications in the extra-thoracic soft tissues presented an opportunity to establish the diagnosis radiologically.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  1. Bacon, J. F.: Arterial calcification in infancy. J. Amer. med. Ass.188, 933 (1964)

    Google Scholar 

  2. Beuren, A. J. Schulz, R., Sinapius, D., Stoermer, J.: Calcinosis of the arteries with coronary calcification in infancy Amer. Heart. J.78, 87 (1969)

    Google Scholar 

  3. Bickel, von E., Janssen, W.: Arteriopathia calcificans infantum. Arch. Kinderheilk.169, 274 (1963)

    Google Scholar 

  4. Bryant, J. H., White, W. H.: A case of calcification of the arteries and obliterative endarteritis, associated with hydronephrosis, in a child aged six months. Guy's Hosp. Rep.55, 17 (1901)

    Google Scholar 

  5. Holm, V.: Arteriopathia calcificans infantum. Acta Paediat. Scand.56, 537 (1967)

    Google Scholar 

  6. Hunt, A. C., Leys, D. G.: Generalized arterial calcification of infancy. Brit. Med. J.1957I, 385

  7. Ivemark, B. I., Lagergren, C., Ljungqvist, A.: Generalized arterial calcification associated with hydramnios in two stillborn infants. Acta Paediat. Suppl.135, 103 (1962)

    Google Scholar 

  8. Khoury, G. H., Hawes, C. R.: Infantile arteriosclerosis. Rocky Mountain Med. J.64, 69 (1967)

    Google Scholar 

  9. Menten, M. L., Fetterman, G. H.: Coronary sclerosis in infancy. Report of three autopsied cases, two in siblings. Amer. J. Clin. Path.18, 805 (1948)

    Google Scholar 

  10. Meurman, L., Somersalo, O., Tuuteri, L.: Sudden death in infancy caused by idiopathic arterial calcification. Ann. Paediat. Fenn.11, 19 (1965)

    Google Scholar 

  11. Meyer, W. W., Lind, J.: Calcifications of the carotid siphon — a common finding in infancy and childhood. Arch. Dis. Childh.47, 355 (1972)

    Google Scholar 

  12. Meyer, W. W., Lind, J.: Calcifications of iliac arteries in newborns and infants. Arch. Dis. Childh.47, 364 (1972)

    Google Scholar 

  13. Moran, J. J., Becker, S. M.: Idiopathic arterial calcification of infancy. Report of 2 cases occurring in siblings, and review of the literature. Amer. J. Clin. Path.31, 517 (1959)

    Google Scholar 

  14. Moran, J. J., Steiner, G. C.: Idiopathic arterial calcification in a 5-year old child. A case report. Amer. J. Clin. Path.37, 521 (1962)

    Google Scholar 

  15. Newman, H., Bregman, E. H.: Neonatal vascular calcification. Southwestern Med.48, 47 (1967)

    Google Scholar 

  16. Parker, R. J., Smith, E. H., Stoneman, M. E. R.: Generalized arterial calcification of infancy. Clin. Radiol.22, 69 (1971)

    Google Scholar 

  17. Prior, J. T., Bergstrom, V. W.: Generalized arterial calfification in infants. Amer. J. Dis. Child.76, 91 (1948)

    Google Scholar 

  18. Raphael, S. S., Horne, W. I., Hyde, T. A.: Arterial medial calcification of infancy in brothers. Can. Med. Ass. J.103, 290 (1970)

    Google Scholar 

  19. Rosenfield, R. L., Breibart, S., Isaacs, H., Jr., Klevit, H. D., Mellman, W. J.: Trisomy of chromosomes 13–15 and 17–18: Its association with infantile arteriosclerosis. Amer. J. Med. Sci.244, 763 (1962)

    Google Scholar 

  20. Sladden, R. A.: Coronary arteriosclerosis and calcification in infancy. J. Clin. Path.5, 175 (1952)

    Google Scholar 

  21. Stryker, W. A.: Arterial calcification in infancy with special reference to the coronary arteries. Amer. J. Path.22, 1007 (1946)

    Google Scholar 

  22. Weens, H. S., Marin, C. A.: Infantile arteriosclerosis. Radiology67, 168 (1956)

    Google Scholar 

  23. Witzleben, C. L.: Idiopathic infantile arterial calcification — A misnomer? Amer. J. Cardiol.26, 305 (1970)

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Lussier-Lazaroff, J., Fletcher, B.D. Idiopathic infantile arterial calcification: Roentgen diagnosis of a rare cause of coronary artery occlusion. Pediatr Radiol 1, 224–228 (1973). https://doi.org/10.1007/BF00972856

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF00972856

Key Words

Navigation