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Functional derivatives of thiophenes

X. Synthesis of derivatives of thieno[2,3-d]pyrimidine and 2,3-polymethylene-4-oxopyrimidine

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Chemistry of Heterocyclic Compounds Aims and scope

Abstract

2,3-Polymethylene-4-oxo-3,4-dihydrothieno[2,3-d]pyrimidine derivatives were obtained by reaction of esters of α-aminothiophene-β-carboxylic acids with lactame or α-aminothiophene-Β-carboxylic acids with lactims. Desulfuration of the thienopyrimidines obtained in this manner is a convenient method for the synthesis of pyrrolo-, pyrido-, and azepino[1,2-a]pyrimidine derivatives.

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Literature cited

  1. V. I. Shvedov, I. A. Kharizomenova, O. B. Romanova, V. K. Vasil'eva, and A. N. Grinev, Khim. Geterotsikl. Soedin., 1204 (1974).

  2. V. I. Shvedov, V. K. Ryzhkova, and A. N. Grinev, Khim. Geterotsikl. Soedin., 459 (1967).

  3. V. I. Shvedov, I. A. Kharizomenova, and A. N. Grinev, Khim. Geterotsikl. Soedin., 58 (1974).

  4. M. V. Telezhenetskaya, Kh. N. Khashimov, and S. Yu. Yunosov, Khim. Prirodn. Soedin., 849 (1971).

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See [1] for communication IX.

Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 6, pp. 765–766, June, 1975.

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Shvedov, V.I., Kharizomenova, I.A. & Grinev, A.N. Functional derivatives of thiophenes. Chem Heterocycl Compd 11, 664–665 (1975). https://doi.org/10.1007/BF00959956

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  • DOI: https://doi.org/10.1007/BF00959956

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