Chemistry of Heterocyclic Compounds

, Volume 10, Issue 4, pp 447–449 | Cite as

Indole derivatives

XCII. Alkylation of barbituric acids with mannich bases
  • N. N. Suvorov
  • V. S. Velezheva
  • V. V. Vampilova
  • E. N. Gordeev


5-Substituted (butyl, phenyl)-5-skatyl(5-methoxyskatyl)barbituric acids were obtained by alkylation of the corresponding barbituric acids with gramine and 5-methoxygramine in dimethylformamide and dimethyl sulfoxide. 5,5-Dialkylation products were obtained in the alkylation of barbituric and thiobarbituric acids with gramine.


Organic Chemistry Phenyl Dimethyl Indole Butyl 
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Copyright information

© Plenum Publishing Corporation 1975

Authors and Affiliations

  • N. N. Suvorov
    • 1
  • V. S. Velezheva
    • 1
  • V. V. Vampilova
    • 1
  • E. N. Gordeev
    • 1
  1. 1.D. I. Mendeleeva Moscow Institute of Chemical TechnologyUSSR

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