Chemistry of Heterocyclic Compounds

, Volume 10, Issue 4, pp 437–442 | Cite as

Semicarbazones and thiosemicarbazones of the heterocyclic series

XXVII. Spectra and structure of isatinΒ-thiosemicarbazones
  • A. B. Tomchin
  • I. S. Ioffe
  • A. I. Kol'tsov
  • Yu. V. Lepp


IsatinΒ-thiosemicarbazone and its alkyl derivatives containing a hydrogen atom attached to N(2′) exist primarily in the form of the syn isomer stabilized by intramolecular hydrogen bonding in solutions and in the crystalline state. The strength of this hydrogen bond increases when both hydrogen atoms in the primary thioamide group are replaced by alkyl groups.


Hydrogen Hydrogen Bond Organic Chemistry Hydrogen Atom Alkyl Group 
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Copyright information

© Plenum Publishing Corporation 1975

Authors and Affiliations

  • A. B. Tomchin
    • 1
  • I. S. Ioffe
    • 1
  • A. I. Kol'tsov
    • 1
  • Yu. V. Lepp
    • 1
  1. 1.S. M. Kirov Military Medical AcademyLeningrad

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