Abstract
2-Acetyl-10-aryl-1,2,3,4-tetrahydrobenzo[b]-1,6-naphthyridines were obtained by reaction of 4′-(2′)-R-2-aminobenzophenones with 1-acetyl-4-piperidone, and their pKa values were determined. It was found that they are oxidized by hydrogen peroxide to give the corresponding N-oxides in good yields. The N-oxides are converted to the 4-acetoxy derivatives by the action of acetic anhydride.
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See [1] for communication VII.
Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 10, pp. 1383–1385, October, 1976.
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Khaldeeva, V.A., Konshin, M.E. Investigation of naphthyridines. Chem Heterocycl Compd 12, 1144–1146 (1976). https://doi.org/10.1007/BF00945602
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DOI: https://doi.org/10.1007/BF00945602