Abstract
The Favorskii reaction with 1,2,5-trimethyl-4-piperidone and ethyl- and naphthylacetylenes gave the corresponding piperidols, the hydrogenation of which gave 1,2,5-trimethyl-4-nbutyl(or 2-naphthylethyl)-4-piperidols. 4-Phenyl- and 4-butyl-2,5-dimethylpyridine were condensed with formaldehyde, and some of the transformations of the resultingβ-hydroxyethyl derivatives were studied.
Similar content being viewed by others
Literature cited
I. N. Nazarov, V. Ya. Raigorodskaya, and V. A. Rudenko, Izv. Akad. Nauk SSSR, Otd. Khim. Nauk, 505 (1949).
I. N. Nazarov and N. S. Prostakov, Zh. Obshch. Khim.,26, 2834 (1956).
N. S. Prostakov, L. A. Gaivoronskaya, N. N. Mikheeva, and N. P. Filippova, Zh. Obshch. Khim.,33, 2928 (1963).
N. S. Prostakov and L. A. Gaivoronskaya, Zh. Obshch. Khim.,32, 76 (1962).
Author information
Authors and Affiliations
Additional information
Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 3, pp. 349–352, March, 1973.
Rights and permissions
About this article
Cite this article
Prostakov, N.S., Kholdarova, T., Pleshakov, V.G. et al. Condensation of 1,2,5-trimethyl-4-piperidone with ethyl- and naphthylacetylenes and synthesis of substituted pyridines. Chem Heterocycl Compd 9, 323–326 (1973). https://doi.org/10.1007/BF00944506
Received:
Issue Date:
DOI: https://doi.org/10.1007/BF00944506