Abstract
The synthesis of the previously unknown 7-bromobenzo[2,1–3]thiadiazole-4-sulfonic acid, its acid chloride and amides, and the corresponding sulfinic acid, which was subsequently converted to the ethylsulfonyl derivative, is described. It is shown that the bromine in amides of 7-bromobenzo[2,1,3]thiadiazole-4-sulfonic acid and the corresponding 4-ethylsuifonyl derivative is readily replaced by an amine.
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V. G. Pesin, I. A. Belen'kaya-Lotsmanenko, and A. M. Khaletskii, Zh. Obshch. Khim.,34, 1267 (1964).
U. S. Patent No. 2,983,730 (1961); Ref. Zh. Khim., 12L212 (1962).
V. G. Pesin and R. S. Muravnik, Izv. Akad. Nauk Latv. SSR, Ser. Khim., 223 (1965).
K. Pilgram, M. Zupan, and R. Skiles, J. Heterocycl. Chem.,7, 629 (1970).
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The author thanks A. F. Bekhli for his useful discussion of the results of this study and V. F. Gladkikh, S. A. Rabinovich, and Professor A. I. Krotov for performing the pharmacological, antimalarial, and antihelminthic investigations of the synthesized compounds.
Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 3, pp. 319–321, March, 1973.
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Mikhailitsyn, F.S. Syntheses in the benzo[2,1,3]thiadiazole series. Chem Heterocycl Compd 9, 293–295 (1973). https://doi.org/10.1007/BF00944497
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DOI: https://doi.org/10.1007/BF00944497