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2-Bromomethyl derivatives of benzofuran and indole and their reactions with some nucleophilic reagents

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Chemistry of Heterocyclic Compounds Aims and scope

Abstract

The corresponding 2-bromomethyl derivatives of benzofuran and indole were obtained by bromination of 2-methyl-3-carbethoxy-5-methoxybenzofuran and 1,2-dimethyl-3-earbethoxy-5-methoxyindole with N-bromosuccinimide. A number of alkyl(aryl)thiomethyl and dialkylaminomethyl derivatives were obtained by reaction of the 2-bromomethyl derivatives with nucleophilic reagents.

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Literature cited

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Authors and Affiliations

  1. Scientific-Research Institute of Medical Radiology, Academy of Medical Sciences of the USSR, USSR

    F. A. Trofimov, N. G. Tsyshkova & A. N. Grinev

  2. S. Ordzhonikidze All-Union Scientific-Research Pharmaceutical-Chemistry Institute, Moscow

    F. A. Trofimov, N. G. Tsyshkova & A. N. Grinev

Authors
  1. F. A. Trofimov
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  2. N. G. Tsyshkova
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  3. A. N. Grinev
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Additional information

Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 3, pp. 308–311, March, 1973.

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Trofimov, F.A., Tsyshkova, N.G. & Grinev, A.N. 2-Bromomethyl derivatives of benzofuran and indole and their reactions with some nucleophilic reagents. Chem Heterocycl Compd 9, 282–285 (1973). https://doi.org/10.1007/BF00944494

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  • DOI: https://doi.org/10.1007/BF00944494

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