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Investigation of the products of the reaction of epichlorohydrin with aromatic amines

XVI. 4-Phenyl-1,2,3,4-tetrahydrobenzo[f]quinoline

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Chemistry of Heterocyclic Compounds Aims and scope

Abstract

Heating N-phenyl-2-naphthylamine with epichlorohydrin gives N-phenyl-N-(3-chloro-2-hydroxypropyl)-2-naphthylamine, which is subsequently converted to 4-phenyl-2-hydroxy-1,2,3,4-tetrahydrobenzo[f]quinoline. The latter readily loses a molecule of water.

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Literature cited

  1. S. I. Kutkevichus and V. A. Darashkaite, Khim. Geterotsikl. Soedin., 1224 (1972).

  2. S. I. Kutkevichus and N. N. Vorozhtsov, Jr., Khim. Geterotsikl. Soedin., 549 (1965).

  3. N. N. Vorozhtsov, Jr., and S. I. Kutkevichus, Khim. Geterotsikl. Soedin., 374 (1965).

  4. G. G. Yakobson, A. É. Ioffe, and N. N. Vorozhtsov, Jr., Izv. Sibirsk. Otd. Akad. Nauk SSSR, Ser. Khim., 156 (1963).

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See [1] for communication XV.

Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 9, pp. 1228–1231, September, 1972.

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Kutkevichus, S.I., Milukas, B.I. & Samarskis, E.A. Investigation of the products of the reaction of epichlorohydrin with aromatic amines. Chem Heterocycl Compd 8, 1110–1113 (1972). https://doi.org/10.1007/BF00944225

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  • DOI: https://doi.org/10.1007/BF00944225

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